Extracellular vesicle analysis

A Hendrix, L Lippens, C Pinheiro, C Théry… - Nature Reviews …, 2023 - nature.com
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …

Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance

P Stejskal, H Goodarzi, J Srovnal, M Hajdúch… - Molecular cancer, 2023 - Springer
Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Clinical applications of stem cell-derived exosomes

F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal Transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

The biology and function of extracellular vesicles in immune response and immunity

R Kalluri - Immunity, 2024 - cell.com
Extracellular vesicles (EVs), such as ectosomes and exosomes, contain DNA, RNA, proteins
and are encased in a phospholipid bilayer. EVs provide intralumenal cargo for delivery into …

[HTML][HTML] Bacterial extracellular vesicles-based therapeutic strategies for bone and soft tissue tumors therapy

H Liu, H Zhang, Y Han, Y Hu, Z Geng, J Su - Theranostics, 2022 - ncbi.nlm.nih.gov
Bone and soft tissue tumors are complex mesenchymal neoplasms that seriously endanger
human health. Over the past decade, the relationship between microorganisms and human …

Emergence of extracellular vesicles as “liquid biopsy” for neurological disorders: boom or bust

A Kumar, MA Nader, G Deep, A Baker - Pharmacological reviews, 2024 - Elsevier
Extracellular vesicles (EVs) have emerged as an attractive liquid biopsy approach in the
diagnosis and prognosis of multiple diseases and disorders. The feasibility of enriching …

L1CAM‐associated extracellular vesicles: A systematic review of nomenclature, sources, separation, and characterization

DE Gomes, KW Witwer - Journal of Extracellular Biology, 2022 - Wiley Online Library
When released into biological fluids like blood or saliva, brain extracellular vesicles (EVs)
might provide a window into otherwise inaccessible tissue, contributing useful biomarkers of …

[HTML][HTML] Engineered bacterial extracellular vesicles for osteoporosis therapy

H Liu, M Li, T Zhang, X Liu, H Zhang, Z Geng… - Chemical Engineering …, 2022 - Elsevier
Osteoporosis (OP) is a systemic bone disease characterized by reduction of bone mass and
destruction of structure, which can easily lead to fragility fractures. Over the past decade, an …

A systematic review and meta‐analysis of clinical trials assessing safety and efficacy of human extracellular vesicle‐based therapy

M Van Delen, J Derdelinckx, K Wouters… - Journal of …, 2024 - Wiley Online Library
Nowadays, it has become clear that extracellular vesicles (EVs) are not a cellular waste
disposal vesicle but are an essential part of an intercellular communication system. Besides …