Importance The incidence of syphilis in the United States is increasing; it is estimated that
more than 55 000 new infections will occur in 2014. Treatment regimens are controversial …

Syphilis is caused by infection with the spirochetal bacterium Treponema subspecies
pallidum. T pallidum is a highly motile coiled organism with tapering ends and 6 to 14 …

Background: Syphilis is a systemic disease from the outset and is caused by the spirochaete
Treponema pallidum. The infection can be classified as congenital (transmitted from mother …

Background Syphilis remains a global public health threat and can lead to severe
complications. In addition to resolution of clinical manifestations, a reduction in …

Background We examined relationships between schistosome infection, HIV transmission or
acquisition, and all-cause death. Methods We retrospectively tested baseline sera from a …

A panel of experts generated 8 “key questions” in the management of adult syphilis. A
systematic literature review was conducted and tables of evidence were constructed to …

Background The optimal treatment of early syphilis (primary, secondary and early latent) in
HIV-infected patients remains controversial. The Center for Diseases Control STD Treatment …

Background We present temporal trends in self-reported and biological markers of
unprotected sex and sex with concurrent partners in discordant couples receiving couples' …

Female sex workers (FSWs) were recruited from known hotspots in Kigali, Rwanda, and
offered free, anonymous human immunodeficiency virus (HIV) counseling and testing …

Background Studies have demonstrated the role of ulcerative and non-ulcerative sexually
transmitted infections (STI) in HIV transmission/acquisition risk; less is understood about the …