Antiparasitics in animal health: quo vadis?

PM Selzer, C Epe - Trends in parasitology, 2021 - cell.com
Antiparasitics acting on endo-or ectoparasites represent the second largest segment of the
global animal health market, accounting for 23% of market share. However, relatively few …

A journey through 50 years of research relevant to the control of gastrointestinal nematodes in ruminant livestock and thoughts on future directions

JS Gilleard, AC Kotze, D Leathwick, AJ Nisbet… - International Journal for …, 2021 - Elsevier
This review article provides an historical perspective on some of the major research
advances of relevance to ruminant livestock gastrointestinal nematode control over the last …

Caenorhabditis elegans is a useful model for anthelmintic discovery

AR Burns, GM Luciani, G Musso, R Bagg… - Nature …, 2015 - nature.com
Parasitic nematodes infect one quarter of the world's population and impact all humans
through widespread infection of crops and livestock. Resistance to current anthelmintics has …

The host immune response to gastrointestinal nematode infection in sheep

KM McRae, MJ Stear, B Good… - Parasite immunology, 2015 - Wiley Online Library
Gastrointestinal nematode infection represents a major threat to the health, welfare and
productivity of sheep populations worldwide. Infected lambs have a reduced ability to absorb …

Extensive sheep and goat production: The role of novel technologies towards sustainability and animal welfare

SR Silva, L Sacarrão-Birrento, M Almeida, DM Ribeiro… - Animals, 2022 - mdpi.com
Simple Summary New technologies have been recognized as valuable in controlling,
monitoring, and managing farm animal activities. It makes it possible to deepen the …

Haemonchus contortus resistance to monepantel in sheep

R Van den Brom, L Moll, C Kappert, P Vellema - Veterinary parasitology, 2015 - Elsevier
In a sheep farm in the Netherlands with a suspected Haemonchus contortus resistance to
monepantel (Zolvix®, Novartis Animal Health), a fecal egg count reduction test was carried …

[HTML][HTML] Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor …

AC Kotze, PW Hunt, P Skuce… - International Journal for …, 2014 - Elsevier
Anthelmintic resistance has a great impact on livestock production systems worldwide, is an
emerging concern in companion animal medicine, and represents a threat to our ongoing …

Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia

BA Rosa, T Supali, L Gankpala, Y Djuardi, E Sartono… - Microbiome, 2018 - Springer
Background The human intestine and its microbiota is the most common infection site for soil-
transmitted helminths (STHs), which affect the well-being of~ 1.5 billion people worldwide …

Plant-based natural products for the discovery and development of novel anthelmintics against nematodes

M Liu, SK Panda, W Luyten - Biomolecules, 2020 - mdpi.com
Intestinal parasitic nematodes infect approximately two billion people worldwide. In the
absence of vaccines for human intestinal nematodes, control of infections currently relies …

First report of monepantel Haemonchus contortus resistance on sheep farms in Uruguay

AE Mederos, Z Ramos, GE Banchero - Parasites & vectors, 2014 - Springer
Background On two farms it was noted that after routine treatment with monepantel, fecal
egg counts failed to drop. This was accompanied by lambs mortality due to Haemonchus …