MicroRNAs (miRNAs or miRs) are a class of small non-coding RNAs that negatively regulate
the expression of target genes by interacting with 3′ untranslated regions of target mRNAs …

Oxycodone (oxy) is a semi-synthetic opioid commonly used as a pain medication that is also
a widely abused prescription drug. While very limited studies have examined the effect of in …

The discovery of non-coding RNAs (ncRNAs) has been one of the central findings from early
genomic sequencing studies. Not only was the presence of these genes unknown …

Differential expression of miRNAs occurs in injured proximal nerve stumps and includes
miRNAs that are firstly down-regulated and then gradually up-regulated following nerve …

The peripheral deafness gene Mir96 is expressed in both the cochlea and central auditory
circuits. To investigate whether it plays a role in the auditory system beyond the cochlea, we …

Objective To explore the neuroprotective effect and mechanism of miR-30c in rats with
cerebral ischemia/reperfusion (CI/R) injury. Methods in vivo, miR-30c mimic was transfected …

Abstract A neuropeptidase, neprilysin (NEP), is a major amyloid (Aβ)-degrading enzyme
involved in the pathogenesis of Alzheimer's disease (AD). The olfactory system is affected …

Cadmium (Cd), a ubiquitous toxic heavy metal, with the intractable trait of low degradation,
can induce multiple organ damage. Whereas, far less is known about its neurotoxicity and …

It is well known that the development of neurodegeneration, and especially Alzheimer's
disease (AD), is often accompanied by impaired olfaction which precedes memory loss. A …

Analysis of the age-related dynamics of olfactory behavior in the odor preference and food
search testsshowed that all male Wistar rats, regardless of age, preferred valerian essential …