Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS)
which initiates rapid signal transmission in the synapse before its re-uptake into the …

Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with onset in
childhood. The mechanisms underlying ASD are unclear. In recent years, the role of …

A distinct pathology for autism spectrum disorder (ASD) remains elusive. Human and animal
studies have focused on investigating the role of neurons in ASD. However, recent studies …

Complex roles for astrocytes in health and disease continue to emerge, highlighting this
class of cells as integral to function and dysfunction of the nervous system. In particular …

Over the last few years, awareness of autism spectrum disorder (ASD) in adults has
increased. The precise etiology of ASD is still unresolved. Animal research, genetic and …

Autism spectrum disorder (ASD) is a sort of mental disorder marked by deficits in cognitive
and communication abilities. To date no effective cure for this pernicious disease has been …

In the last decades, astrocytes have risen from passive supporters of neuronal activity to
central players in brain function and cognition. Likewise, the heterogeneity of astrocytes …

The generation of astrocytes from human induced pluripotent stem cells has been hampered
by either prolonged differentiation—spanning over two months—or by shorter protocols that …

This paper reviews the potential role of glutathione (GSH) in autism spectrum disorder
(ASD). GSH plays a key role in the detoxification of xenobiotics and maintenance of balance …

Significant efforts are increasingly directed towards identifying novel therapeutic targets for
autism spectrum disorder (ASD) with a rising role of aberrant glutamatergic transmission in …