Phototherapeutic anticancer strategies with first-row transition metal complexes: a critical review
Photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) are therapeutic
techniques based on a photosensitizer (PS) and light. These techniques allow the spatial …
techniques based on a photosensitizer (PS) and light. These techniques allow the spatial …
The medicinal chemistry of ferrocene and its derivatives
Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …
Advances in copper complexes as anticancer agents
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …
A new age for iron: antitumoral ferrocenes
From the core of the earth to the core of the archetypal organometallic compound ferrocene,
iron and its compounds contribute to create many aspects of our reality: the earth's …
iron and its compounds contribute to create many aspects of our reality: the earth's …
Novel mitochondria targeted copper (II) complexes of ferrocenyl terpyridine and anticancer active 8-hydroxyquinolines showing remarkable cytotoxicity, DNA and …
B Deka, T Sarkar, S Banerjee, A Kumar… - Dalton …, 2017 - pubs.rsc.org
Metal complexes with organelle specificity and potent but selective cytotoxicity are highly
desirable. In this work, we report the synthesis, characterization and cytotoxicity of six novel …
desirable. In this work, we report the synthesis, characterization and cytotoxicity of six novel …
Metallomics insights into the programmed cell death induced by metal-based anticancer compounds
Since the discovery of cisplatin more than 40 years ago, enormous research efforts have
been dedicated to developing metal-based anticancer agents and to elucidating the …
been dedicated to developing metal-based anticancer agents and to elucidating the …
Monitoring of the ADP/ATP ratio by induced circularly polarised europium luminescence
A series of three europium complexes bearing picolyl amine moieties was found to possess
differing binding affinities towards Zn2+ and three nucleotides: AMP, ADP, and ATP. A large …
differing binding affinities towards Zn2+ and three nucleotides: AMP, ADP, and ATP. A large …
Terpyridines as promising antitumor agents: An overview of their discovery and development
R Musiol, P Malecki, M Pacholczyk… - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction The fused aromatic system of terpyridines makes them good, innocent ligands
for various metals. The resulting complexes have been extensively studied for both their …
for various metals. The resulting complexes have been extensively studied for both their …
Antitumor activity of synthetic three copper (II) complexes with terpyridine ligands
Y Yang, FF Guo, CF Chen, YL Li, H Liang… - Journal of Inorganic …, 2023 - Elsevier
Three new synthetic terpyridine copper (II) complexes were characterized. The copper (II)
complexes induced apoptosis of three cancer cell lines and arrested T-24 cell cycle in G1 …
complexes induced apoptosis of three cancer cell lines and arrested T-24 cell cycle in G1 …
Photocytotoxicity of copper (II) complexes of curcumin and N-ferrocenylmethyl-L-amino acids
Copper (II) complexes [Cu (Fc-aa)(cur)](1–3) of curcumin (Hcur) and N-ferrocenylmethyl-l-
amino acids (Fc-aa), viz., ferrocenylmethyl-l-tyrosine (Fc-TyrH), ferrocenylmethyl-l …
amino acids (Fc-aa), viz., ferrocenylmethyl-l-tyrosine (Fc-TyrH), ferrocenylmethyl-l …