Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …

Benzothiazole is an organic compound bearing a heterocyclic nucleus (thiazole) which
imparts a broad spectrum of biological activities to it. The significant and potent activity of …

Fluorine-containing heterocycles continue to receive considerable attention due to their
unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules …

On the pharmaceutical account of the reported anticancer activity of benzothiazole
derivatives, differently substituted benzothiazole derivatives 2a–c to 34a, b, attached at 2 …

Background The numbers of topoisomerase I targeted drugs on the market are very limited
although they are used clinically for treatment of solid tumors. Hence, studies about finding …

A new mixed ligand copper (II)-dipeptide complex with 2-(2′-pyridyl) benzothiazole
(pbt),[Cu (Gly-L-leu)(pbt)(H 2 O)]· ClO 4 (Gly-L-leu= Glycyl-L-leucine anion) was synthesized …

Novel DNA binding agents against topoisomerases are needed for effective treatment of
cancers. A series of new acridine-based derivatives 7a–7d were synthesized and their …

Two new hybrid half‐sandwiched Ru (II) arene complexes of a general formula [η 6-(p-
cymene) Ru (L) Cl](4a, b){where L= 1-(Benzazol-2-yl)-3-(thiophen-2-yl) propane-1, 3-dione} …

There has been considerable interest in DNA topoisomerases over the last decade, as they
have been shown to be one of the major cellular targets in anticancer drug development …

Objective: This study aimed synthesis of benzothiazole and thiazole derivatives due to the
importance of these heterocycles as anticancer. Method: Novel benzothiazole and thiazole …