Sex differences in arterial hypertension: a scientific statement from the ESC Council on Hypertension, the European Association of Preventive Cardiology, Association …

E Gerdts, I Sudano, S Brouwers, C Borghi… - European Heart …, 2022 - academic.oup.com
There is strong evidence that sex chromosomes and sex hormones influence blood
pressure (BP) regulation, distribution of cardiovascular (CV) risk factors and co-morbidities …

Sex differences in mechanisms of arterial stiffness

JJ DuPont, RM Kenney, AR Patel… - British journal of …, 2019 - Wiley Online Library
Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …

Vascular stiffness in aging and disease

SF Vatner, J Zhang, C Vyzas, K Mishra… - Frontiers in …, 2021 - frontiersin.org
The goal of this review is to provide further understanding of increased vascular stiffness
with aging, and how it contributes to the adverse effects of major human diseases …

Characterization of the inflammatory‐metabolic phenotype of heart failure with a preserved ejection fraction: a hypothesis to explain influence of sex on the evolution …

M Packer, CSP Lam, LH Lund… - European Journal of …, 2020 - Wiley Online Library
Accumulating evidence points to the existence of an inflammatory‐metabolic phenotype of
heart failure with a preserved ejection fraction (HFpEF), which is characterized by …

Cellular mechanisms underlying obesity-induced arterial stiffness

AR Aroor, G Jia, JR Sowers - American Journal of …, 2018 - journals.physiology.org
Obesity is an emerging pandemic driven by consumption of a diet rich in fat and highly
refined carbohydrates (a Western diet) and a sedentary lifestyle in both children and adults …

Carotid stiffness is associated with incident stroke: a systematic review and individual participant data meta-analysis

TT Van Sloten, S Sedaghat, S Laurent… - Journal of the American …, 2015 - jacc.org
Background: Carotid stiffening is considered a key element in the pathogenesis of stroke.
However, results of studies evaluating the association between carotid stiffness and incident …

Sex‐specific cardiovascular structure and function in heart failure with preserved ejection fraction

M Gori, CSP Lam, DK Gupta… - European journal of …, 2014 - Wiley Online Library
Aims Women are more likely to develop heart failure with preserved ejection fraction
(HFpEF) than men. We studied the relationship between sex and cardiovascular structure …

Estrogen-related mechanisms in sex differences of hypertension and target organ damage

AR Sabbatini, G Kararigas - Biology of sex differences, 2020 - Springer
Hypertension (HTN) is a primary risk factor for cardiovascular (CV) events, target organ
damage (TOD), premature death and disability worldwide. The pathophysiology of HTN is …

The role of tissue renin-angiotensin-aldosterone system in the development of endothelial dysfunction and arterial stiffness

AR Aroor, VG DeMarco, G Jia, Z Sun… - Frontiers in …, 2013 - frontiersin.org
Epidemiological studies support the notion that arterial stiffness is an independent predictor
of adverse cardiovascular events contributing significantly to systolic hypertension, impaired …

The critical role of pulmonary arterial compliance in pulmonary hypertension

T Thenappan, KW Prins, MR Pritzker… - Annals of the …, 2016 - atsjournals.org
The normal pulmonary circulation is a low-pressure, high-compliance system. Pulmonary
arterial compliance decreases in the presence of pulmonary hypertension because of …