Pattern transitions in spatial epidemics: Mechanisms and emergent properties
Infectious diseases are a threat to human health and a hindrance to societal development.
Consequently, the spread of diseases in both time and space has been widely studied …
Consequently, the spread of diseases in both time and space has been widely studied …
[HTML][HTML] In-host modeling
SM Ciupe, JM Heffernan - Infectious Disease Modelling, 2017 - Elsevier
Understanding the mechanisms governing host-pathogen kinetics is important and can
guide human interventions. In-host mathematical models, together with biological data, have …
guide human interventions. In-host mathematical models, together with biological data, have …
Post-treatment control of HIV infection
JM Conway, AS Perelson - Proceedings of the National …, 2015 - National Acad Sciences
Antiretroviral therapy (ART) for HIV is not a cure. However, recent studies suggest that ART,
initiated early during primary infection, may induce post-treatment control (PTC) of HIV …
initiated early during primary infection, may induce post-treatment control (PTC) of HIV …
[HTML][HTML] Stability of delayed HIV dynamics models with two latent reservoirs and immune impairment
The purpose of this paper is to investigate the qualitative behavior of HIV dynamics models
with immune impairment. The HIV particles infect both CD4+ T cells and macrophages. Both …
with immune impairment. The HIV particles infect both CD4+ T cells and macrophages. Both …
Mathematical analysis of a delayed HIV infection model with saturated CTL immune response and immune impairment
Y Yang, R Xu - Journal of Applied Mathematics and Computing, 2022 - Springer
In this paper, we develop an HIV infection model with intracellular delay, Beddington–
DeAngelis incidence rate, saturated CTL immune response and immune impairment. We …
DeAngelis incidence rate, saturated CTL immune response and immune impairment. We …
[HTML][HTML] Dynamics analysis of a delayed viral infection model with immune impairment
S Wang, X Song, Z Ge - Applied Mathematical Modelling, 2011 - Elsevier
In this paper, the dynamical behavior of a delayed viral infection model with immune
impairment is studied. It is shown that if the basic reproductive number of the virus is less …
impairment is studied. It is shown that if the basic reproductive number of the virus is less …
The effect of noise in an HIV infection model with cytotoxic T-lymphocyte impairment
A Majumder, S Sardar, N Bairagi - Chaos: An Interdisciplinary Journal …, 2022 - pubs.aip.org
The human immunodeficiency virus (HIV) interacts with the immune cells within the human
body, where the environment is uncertain and noisy. Stochastic models can successfully …
body, where the environment is uncertain and noisy. Stochastic models can successfully …
Modeling the immune response to HIV infection
JM Conway, RM Ribeiro - Current opinion in systems biology, 2018 - Elsevier
The interplay between immune response and HIV is intensely studied via mathematical
modeling, with significant insights but few direct answers. In this short review, we highlight …
modeling, with significant insights but few direct answers. In this short review, we highlight …
HIV evolution and progression of the infection to AIDS
G Huang, Y Takeuchi, A Korobeinikov - Journal of theoretical biology, 2012 - Elsevier
In this paper, we propose and discuss a possible mechanism, which, via continuous
mutations and evolution, eventually enables HIV to break from immune control. In order to …
mutations and evolution, eventually enables HIV to break from immune control. In order to …
Analysis of time delay in viral infection model with immune impairment
P Krishnapriya, M Pitchaimani - Journal of Applied Mathematics and …, 2017 - Springer
In this paper, a class of virus infection models with CTLs response is considered. We
incorporate three delays with immune impairment into the virus infection model. We begin …
incorporate three delays with immune impairment into the virus infection model. We begin …