Epigenetic regulation in breast cancer: Insights on epidrugs

A Kim, K Mo, H Kwon, S Choe, M Park, W Kwak… - Epigenomes, 2023 - mdpi.com
Breast cancer remains a common cause of cancer-related death in women. Therefore,
further studies are necessary for the comprehension of breast cancer and the revolution of …

Unraveling therapeutic opportunities and the diagnostic potential of microRNAs for human lung cancer

O Sweef, E Zaabout, A Bakheet, M Halawa, I Gad… - Pharmaceutics, 2023 - mdpi.com
Lung cancer is a major public health problem and a leading cause of cancer-related deaths
worldwide. Despite advances in treatment options, the five-year survival rate for lung cancer …

[HTML][HTML] LncRNA TTN-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis

D Fu, C Lu, X Qu, P Li, K Chen, L Shan, X Zhu - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Aim: To explore the mechanism by which long non-coding RNA (lncRNA) TTN-AS1
regulates osteosarcoma cell apoptosis and drug resistance via the microRNA miR-134 …

miR-145-5p suppresses proliferation, metastasis and EMT of colorectal cancer by targeting CDCA3

Q Chen, L Zhou, X Ye, M Tao, J Wu - Pathology-Research and Practice, 2020 - Elsevier
MicroRNAs play a critical role in regulating the carcinogenesis of colorectal cancer (CRC).
Even though its role is unclear in CRC, miR-145-5p has been reported to have anti …

Establishing mechanisms affecting the individual response to ionizing radiation

D Averbeck, S Candéias, S Chandna… - … Journal of Radiation …, 2020 - Taylor & Francis
Purpose: Humans are increasingly exposed to ionizing radiation (IR). Both low (< 100 mGy)
and high doses can cause stochastic effects, including cancer; whereas doses above 100 …

Double-edged sword role of miRNA-633 and miRNA-181 in human cancers

J Gupta, M Suliman, R Ali, R Margiana, A Hjazi… - … -Research and Practice, 2023 - Elsevier
Understanding the function and mode of operation of microRNAs (miRNAs) in cancer is of
growing interest. The short non-coding RNAs known as miRNAs, which target mRNA in …

All-trans retinoic acid-mediated miR-30a up-regulation suppresses autophagy and sensitizes gastric cancer cells to cisplatin

A Abbasi, M Hosseinpourfeizi, R Safaralizadeh - Life Sciences, 2022 - Elsevier
Aims The potential of all-trans retinoic acid (ATRA) in regulating some microRNAs (miRNAs)
involved in multiple cancer-related pathways, including resistance to chemotherapeutics …

MicroRNAs that regulate PTEN as potential biomarkers in colorectal cancer: a systematic review

J Liu, F Ke, T Chen, Q Zhou, L Weng, J Tan… - Journal of cancer …, 2020 - Springer
Purpose MicroRNAs (miRNAs) participate in a variety of biological processes, including
tumorigenesis, progression, invasion, and drug resistance to multiple cancers. Phosphatase …

A novel protective role for microRNA-3135b in Golgi apparatus fragmentation induced by chemotherapy via GOLPH3/AKT1/mTOR axis in colorectal cancer cells

SI Núñez-Olvera, B Chavez-Munguia… - Scientific reports, 2020 - nature.com
Chemotherapy activates a novel cytoplasmic DNA damage response resulting in Golgi
apparatus fragmentation and cancer cell survival. This mechanism is regulated by Golgi …

Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome

X Zhao, X Zhang, Z Wu, J Mei, L Li, Y Wang - Molecular Medicine, 2021 - Springer
Objective Numerous studies have confirmed the correlation of microRNAs (miRNAs) with
human disease, yet few have explored the role of miR-135 in preeclampsia (PE). This study …