Exendin‐4 analogs in insulinoma theranostics
TJP Jansen, SAM van Lith, M Boss… - Journal of Labelled …, 2019 - Wiley Online Library
Insulinomas are neuroendocrine tumors arising from the pancreatic beta cells. Currently,
surgical resection is the therapy of choice, and therefore, preoperative localization of …
surgical resection is the therapy of choice, and therefore, preoperative localization of …
Nanomedicine-based strategies for diabetes: diagnostics, monitoring, and treatment
Traditional methods for diabetes management require constant and tedious glucose
monitoring (GM) and insulin injections, impacting quality of life. The global diabetic …
monitoring (GM) and insulin injections, impacting quality of life. The global diabetic …
Non-invasive beta-cell imaging: Visualization, quantification, and beyond
T Murakami, H Fujimoto, N Inagaki - Frontiers in Endocrinology, 2021 - frontiersin.org
Pancreatic beta (β)-cell dysfunction and reduced mass play a central role in the
development and progression of diabetes mellitus. Conventional histological β-cell mass …
development and progression of diabetes mellitus. Conventional histological β-cell mass …
Advances of functional nanomaterials for magnetic resonance imaging and biomedical engineering applications
R Huang, X Zhou, G Chen, L Su, Z Liu… - Wiley …, 2022 - Wiley Online Library
Functional nanomaterials have been widely used in biomedical fields due to their good
biocompatibility, excellent physicochemical properties, easy surface modification, and easy …
biocompatibility, excellent physicochemical properties, easy surface modification, and easy …
In Vivo Bioengineering of Beta Cells with Immune Checkpoint Ligand as a Treatment for Early-Onset Type 1 Diabetes Mellitus
Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by autoreactive T cells
targeting the insulin-producing beta (β) cells. Despite advances in insulin therapy, T1DM still …
targeting the insulin-producing beta (β) cells. Despite advances in insulin therapy, T1DM still …
Liraglutide, a human glucagon‐like peptide‐1 analogue, stimulates AKT‐dependent survival signalling and inhibits pancreatic β‐cell apoptosis
K Kapodistria, EP Tsilibary… - Journal of Cellular …, 2018 - Wiley Online Library
Liraglutide, a human long‐lasting GLP‐1 analogue, is currently regarded as a powerful
treatment option for type 2 diabetes. Apart from glucoregulatory and insulinotropic actions …
treatment option for type 2 diabetes. Apart from glucoregulatory and insulinotropic actions …
Mouse models and human islet transplantation sites for intravital imaging
LE Wagner, O Melnyk, BE Duffett… - Frontiers in …, 2022 - frontiersin.org
Human islet transplantations into rodent models are an essential tool to aid in the
development and testing of islet and cellular-based therapies for diabetes prevention and …
development and testing of islet and cellular-based therapies for diabetes prevention and …
Molecular imaging of β-cells: diabetes and beyond
W Wei, EB Ehlerding, X Lan, QY Luo, W Cai - Advanced drug delivery …, 2019 - Elsevier
Since diabetes is becoming a global epidemic, there is a great need to develop early β-cell
specific diagnostic techniques for this disorder. There are two types of diabetes (ie, type 1 …
specific diagnostic techniques for this disorder. There are two types of diabetes (ie, type 1 …
miR-216a-targeting theranostic nanoparticles promote proliferation of insulin-secreting cells in type 1 diabetes animal model
Aberrant expression of miRNAs in pancreatic islets is closely related to the development of
type 1 diabetes (T1D). The aim of this study was to identify key miRNAs dysregulated in …
type 1 diabetes (T1D). The aim of this study was to identify key miRNAs dysregulated in …
Targeting β cells with cathelicidin nanomedicines improves insulin function and pancreas regeneration in type 1 diabetic rats
C Cristelo, R Nunes, S Pinto, JM Marques… - ACS Pharmacology & …, 2023 - ACS Publications
Type 1 diabetes (T1D) is an incurable condition with an increasing incidence worldwide, in
which the hallmark is the autoimmune destruction of pancreatic insulin-producing β cells …
which the hallmark is the autoimmune destruction of pancreatic insulin-producing β cells …