Bile acids play key roles in gut metabolism, cell signaling, and microbiome composition.
While the liver is responsible for the production of primary bile acids, microbes in the gut …

Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

Bile acids are synthesized from cholesterol in the liver and released into the intestine to aid
the digestion of dietary lipids. The host enzymes that contribute to bile acid synthesis in the …

Primary bile acids serve important roles in cholesterol metabolism, lipid digestion, host-
microbe interactions, and regulatory pathways in the human host. While most bile acids are …

Primary bile acids (BAs) are a collection of host-synthesized metabolites that shape
physiology and metabolism. BAs transit the gastrointestinal tract and are subjected to a …

Bile salt hydrolases (BSHs) catalyze the “gateway” reaction in a wider pathway of bile acid
modification by the gut microbiota. Because bile acids function as signaling molecules …

Bile acids (BA), the major components of bile, are biological detergents that facilitate the
emulsification and solubilization of dietary lipids and also display potent antimicrobial …

Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts
is often precluded by practical, economical and ethical reasons and mice are widely used …

Gut microbiota and their metabolites like bile acid (BA) have been investigated as causes of
irritable bowel syndrome (IBS) symptoms. Primary BAs are synthesized and conjugated in …

The field of bile acid microbiology in the gastrointestinal tract is going through a current
rebirth after a peak of activity in the late 1970s and early 1980s. This renewed activity is a …