Glycosylation in health and disease

C Reily, TJ Stewart, MB Renfrow, J Novak - Nature Reviews Nephrology, 2019 - nature.com
The glycome describes the complete repertoire of glycoconjugates composed of
carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules …

Mitochondrial quality control mechanisms as molecular targets in diabetic heart

X Chang, Y Li, C Cai, F Wu, J He, Y Zhang, J Zhong… - Metabolism, 2022 - Elsevier
Mitochondrial dysfunction has been regarded as a hallmark of diabetic cardiomyopathy. In
addition to their canonical metabolic actions, mitochondria influence various other aspects of …

Diabesity: the combined burden of obesity and diabetes on heart disease and the role of imaging

ACT Ng, V Delgado, BA Borlaug, JJ Bax - Nature Reviews Cardiology, 2021 - nature.com
Diabesity is a term used to describe the combined adverse health effects of obesity and
diabetes mellitus. The worldwide dual epidemic of obesity and type 2 diabetes is an …

Diabetic cardiomyopathy-a comprehensive updated review

G Murtaza, HUH Virk, M Khalid, CJ Lavie… - Progress in …, 2019 - Elsevier
Diabetes causes cardiomyopathy and increases the risk of heart failure independent of
hypertension and coronary heart disease. This condition called “Diabetic Cardiomyopathy” …

NF-κβ: a potential target in the management of vascular complications of diabetes

SV Suryavanshi, YA Kulkarni - Frontiers in pharmacology, 2017 - frontiersin.org
Diabetes is a metabolic disorder affecting large percentage of population worldwide. NF-κβ
plays key role in pathogenesis of vascular complications of diabetes. Persistent …

Diabetes mellitus, blood glucose and the risk of atrial fibrillation: a systematic review and meta-analysis of cohort studies

D Aune, T Feng, S Schlesinger, I Janszky… - Journal of Diabetes and …, 2018 - Elsevier
Background Diabetes and elevated blood glucose have been associated with increased risk
of atrial fibrillation in a number of epidemiological studies, however, the findings have not …

The diabetic cardiomyopathy: the contributing pathophysiological mechanisms

T Salvatore, PC Pafundi, R Galiero, G Albanese… - Frontiers in …, 2021 - frontiersin.org
Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

The prevalence of left ventricular diastolic dysfunction and heart failure with preserved ejection fraction in men and women with type 2 diabetes: A systematic review …

S Bouthoorn, GB Valstar, A Gohar… - Diabetes and …, 2018 - journals.sagepub.com
Objective: Type 2 diabetes is a risk factor for the development of left ventricular diastolic
dysfunction and heart failure with preserved ejection fraction. Our aim was to provide a …

Mitophagy in cardiovascular diseases

G Morciano, S Patergnani, M Bonora, G Pedriali… - Journal of clinical …, 2020 - mdpi.com
Cardiovascular diseases are one of the leading causes of death. Increasing evidence has
shown that pharmacological or genetic targeting of mitochondria can ameliorate each stage …

Subclinical LV dysfunction and 10-year outcomes in type 2 diabetes mellitus

DJ Holland, TH Marwick, BA Haluska, R Leano… - Heart, 2015 - heart.bmj.com
Objective New imaging techniques have permitted the detection of subclinical LV
dysfunction (LVD) in up to half of patients with type 2 diabetes mellitus (DM) with a normal …