Proper brain development essentially depends on the timed availability of sufficient amounts
of thyroid hormone (TH). This, in turn, necessitates a tightly regulated expression of TH …

In the brain, astrocytes regulate shape and functions of the synaptic and vascular
compartments through a variety of released factors and membrane-bound proteins. An …

A cohort of morphologically heterogenous doublecortin immunoreactive (DCX+)“immature
neurons” has been identified in the cerebral cortex largely around layer II and the amygdala …

Astrocytes strongly promote the formation and maturation of synapses by secreted proteins.
Several astrocyte-secreted synaptogenic proteins controlling excitatory synapse …

Background Consistent with postmortem findings in patients, most animal models for
schizophrenia (SCZ) present abnormal levels of parvalbumin (PV), a marker of fast-spiking …

Mothers exposed to infections during pregnancy disproportionally birth children who
develop autism and schizophrenia, disorders associated with altered GABAergic function …

The adult brain is a complex structure with distinct functional sub-regions, which are
generated from an initial pool of neural epithelial cells within the embryo. This transition …

GABAergic interneurons are key regulators of cortical circuit function. Among the dozens of
reported transcriptionally distinct subtypes of cortical interneurons, neurogliaform cells …

Neurotrophins and their receptors are distinctly expressed during brain development and
play crucial roles in the formation, survival, and function of neurons in the nervous system …

Gestational iron deficiency (gID) is highly prevalent and associated with an increased risk of
intellectual and developmental disabilities in affected individuals that are often defined by a …