Inflammation in sleep apnea: an update

D Unnikrishnan, J Jun, V Polotsky - Reviews in Endocrine and Metabolic …, 2015 - Springer
Obstructive sleep apnea (OSA) is a common disorder associated with cardiovascular
disease (CVD). One theory to explain this relationship proposes that OSA can induce …

Obstructive sleep apnea and hypertension: an update

T Konecny, T Kara, VK Somers - Hypertension, 2014 - Am Heart Assoc
Repetitive OSA-induced hypoxemia and hypercapnia elicit reflex changes in both
sympathetic and parasympathetic activation. 19, 20 These autonomic derangements, with …

The different clinical faces of obstructive sleep apnoea: a cluster analysis

L Ye, GW Pien, SJ Ratcliffe… - European …, 2014 - Eur Respiratory Soc
Although commonly observed in clinical practice, the heterogeneity of obstructive sleep
apnoea (OSA) clinical presentation has not been formally characterised. This study was the …

Obstructive sleep apnea during REM sleep and hypertension. results of the Wisconsin Sleep Cohort

B Mokhlesi, LA Finn, EW Hagen, T Young… - American journal of …, 2014 - atsjournals.org
Rationale: Obstructive sleep apnea (OSA) is associated with hypertension. Objectives: We
aimed to quantify the independent association of OSA during REM sleep with prevalent and …

The effect of sex and age on the comorbidity burden of OSA: an observational analysis from a large nationwide US health claims database

B Mokhlesi, SA Ham, D Gozal - European Respiratory Journal, 2016 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is a highly prevalent condition but studies exploring the
burden of OSA-associated comorbidities have been limited by small sample sizes with …

Effect of CPAP on blood pressure in patients with minimally symptomatic obstructive sleep apnoea: a meta-analysis using individual patient data from four randomised …

DJ Bratton, JR Stradling, F Barbé, M Kohler - Thorax, 2014 - thorax.bmj.com
Background CPAP reduces blood pressure (BP) in patients with symptomatic obstructive
sleep apnoea (OSA). Whether the same benefit is present in patients with minimally …

Effect of CPAP therapy on endothelial function in obstructive sleep apnoea: a systematic review and meta‐analysis

EI Schwarz, MA Puhan, C Schlatzer, JR Stradling… - …, 2015 - Wiley Online Library
Obstructive sleep apnoea (OSA) is a prevalent sleep‐related breathing disorder associated
with adverse cardiovascular outcome. Endothelial dysfunction is one of the proposed …

[HTML][HTML] Obstructive sleep apnea with or without excessive daytime sleepiness: clinical and experimental data-driven phenotyping

S Garbarino, E Scoditti, P Lanteri, L Conte… - Frontiers in …, 2018 - frontiersin.org
Introduction: Obstructive sleep apnea (OSA) is a serious and prevalent medical condition
with major consequences for health and safety. Excessive daytime sleepiness (EDS) is a …

Does obstructive sleep apnea cause endothelial dysfunction? A critical review of the literature

CM Hoyos, KL Melehan, PY Liu, RR Grunstein… - Sleep medicine …, 2015 - Elsevier
Endothelial dysfunction is characterized by impaired endothelium-dependent vasodilatation
and is an independent predictor of adverse cardiovascular consequences. The ease with …

A clinical approach to obstructive sleep apnea as a risk factor for cardiovascular disease

MT Maeder, OD Schoch, H Rickli - Vascular health and risk …, 2016 - Taylor & Francis
Obstructive sleep apnea (OSA) is associated with cardiovascular risk factors, cardiovascular
diseases, and increased mortality. Epidemiological studies have established these …