Profilins are small proteins involved in actin dynamics. In accordance with this function, they
are found in all eukaryotes and are structurally highly conserved. However, their precise role …

Profilins are small actin-binding proteins found in eukaryotes and certain viruses that are
involved in cell development, cytokinesis, membrane trafficking, and cell motility. Originally …

Cells have many types of actin structures, which must assemble from a common monomer
pool. Yet, it remains poorly understood how monomers are distributed to and shared …

Profilin is a ubiquitously expressed protein well known as a key regulator of actin
polymerisation. The actin cytoskeleton is involved in almost all cellular processes including …

This review covers aspects of cofilin and profilin regulations and their influence on actin
polymerisation responsible for cell motility and metastasis. The regulation of their activity by …

Actin and microtubules play essential roles in aberrant cell processes that define and
converge in cancer including: signaling, morphology, motility, and division. Actin and …

Chloroplasts accumulate in response to low light, whereas high light induces an actin-
dependent avoidance movement. This is a long known process, but its molecular base is …

Morphological changes at synaptic specializations have been implicated in regulating
synaptic strength. Actin turnover at dendritic spines is regulated by neuronal activity and …

Angiogenesis, the formation of new blood vessels, is fundamental to development and post-
injury tissue repair. Vascular endothelial growth factor (VEGF)-A guides and enhances …

During respiratory syncytial virus (RSV) infection there is a close physical interaction
between the filamentous actin (F-actin) and the virus, involving both inclusion bodies and …