Oxazolidinones: mechanisms of resistance and mobile genetic elements involved

A Brenciani, G Morroni, S Schwarz… - Journal of …, 2022 - academic.oup.com
The oxazolidinones (linezolid and tedizolid) are last-resort antimicrobial agents used for the
treatment of severe infections in humans caused by MDR Gram-positive bacteria. They bind …

Treatment of Staphylococcus aureus Infections

MZ David, RS Daum - Staphylococcus aureus: microbiology, pathology …, 2017 - Springer
Staphylococcus aureus, although generally identified as a commensal, is also a common
cause of human bacterial infections, including of the skin and other soft tissues, bones …

Antibiotic combinations reduce Staphylococcus aureus clearance

V Lázár, O Snitser, D Barkan, R Kishony - Nature, 2022 - nature.com
The spread of antibiotic resistance is attracting increased attention to combination-based
treatments. Although drug combinations have been studied extensively for their effects on …

Current landscape and future perspective of oxazolidinone scaffolds containing antibacterial drugs

Q Zhao, L Xin, Y Liu, C Liang, J Li, Y Jian… - Journal of Medicinal …, 2021 - ACS Publications
The widespread use of antibiotics has made the problem of bacterial resistance increasingly
serious, and the study of new drug-resistant bacteria has become the main direction of …

The multifaceted lifestyle of enterococci: genetic diversity, ecology and risks for public health

V Cattoir - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Enterococci have become major human MDR nosocomial pathogens.•They are
found ubiquitously in non-human habitats (animals and the environment).•The main threat …

Antimicrobial resistance, virulence genes and biofilm formation in Enterococcus species isolated from milk of sheep and goat with subclinical mastitis

MA El-Zamkan, HMA Mohamed - PloS one, 2021 - journals.plos.org
This study is designed to discuss the antimicrobial resistance, virulence determinants and
biofilm formation capacity of Enterococcus spp. isolated from milk of sheep and goat with …

Selenium nanoparticles as candidates for antibacterial substitutes and supplements against multidrug-resistant bacteria

HW Han, KD Patel, JH Kwak, SK Jun, TS Jang, SH Lee… - Biomolecules, 2021 - mdpi.com
In recent years, multidrug-resistant (MDR) bacteria have increased rapidly, representing a
major threat to human health. This problem has created an urgent need to identify …

Thinking outside the bug: molecular targets and strategies to overcome antibiotic resistance

A Monserrat-Martinez, Y Gambin… - International journal of …, 2019 - mdpi.com
Since their discovery in the early 20th century, antibiotics have been used as the primary
weapon against bacterial infections. Due to their prophylactic effect, they are also used as …

Linezolid resistance genes and genetic elements enhancing their dissemination in enterococci and streptococci

E Sadowy - Plasmid, 2018 - Elsevier
Linezolid is considered a last resort drug in treatment of severe infections caused by Gram-
positive pathogens, resistant to other antibiotics, such as vancomycin-resistant enterococci …

A comprehensive study on the antimicrobial properties of resveratrol as an alternative therapy

E Abedini, E Khodadadi, E Zeinalzadeh… - Evidence‐Based …, 2021 - Wiley Online Library
Resveratrol is a polyphenolic antioxidant whose possible health benefits include
anticarcinogenic, antiaging, and antimicrobial properties that have gained significant …