[HTML][HTML] Introduction to extracellular vesicles: biogenesis, RNA cargo selection, content, release, and uptake

ER Abels, XO Breakefield - Cellular and molecular neurobiology, 2016 - Springer
Extracellular vesicles are a heterogeneous group of membrane-limited vesicles loaded with
various proteins, lipids, and nucleic acids. Release of extracellular vesicles from its cell of …

Exosomes and other extracellular vesicles in host–pathogen interactions

JS Schorey, Y Cheng, PP Singh, VL Smith - EMBO reports, 2015 - embopress.org
An effective immune response requires the engagement of host receptors by pathogen‐
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …

Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles

M Colombo, G Raposo, C Théry - Annual review of cell and …, 2014 - annualreviews.org
In the 1980s, exosomes were described as vesicles of endosomal origin secreted from
reticulocytes. Interest increased around these extracellular vesicles, as they appeared to …

[HTML][HTML] Extracellular vesicles: lipids as key components of their biogenesis and functions

M Record, S Silvente-Poirot, M Poirot… - Journal of Lipid …, 2018 - ASBMB
Intercellular communication has been known for decades to involve either direct contact
between cells or to operate via circulating molecules, such as cytokines, growth factors, or …

[HTML][HTML] The crosstalk: Exosomes and lipid metabolism

W Wang, N Zhu, T Yan, YN Shi, J Chen… - Cell Communication and …, 2020 - Springer
Exosomes have been considered as novel and potent vehicles of intercellular
communication, instead of “cell dust”. Exosomes are consistent with anucleate cells, and …

Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies

M Record, K Carayon, M Poirot… - Biochimica et Biophysica …, 2014 - Elsevier
Exosomes are nanovesicles that have emerged as a new intercellular communication
system between an intracellular compartment of a donor cell towards the periphery or an …

Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants

R Cantin, J Diou, D Bélanger, AM Tremblay… - Journal of immunological …, 2008 - Elsevier
Although enveloped retroviruses bud from the cell surface of T lymphocytes, they use the
endocytic pathway and the internal membrane of multivesicular bodies for their assembly …

[HTML][HTML] Emerging function and clinical significance of exosomal circRNAs in cancer

M Wang, F Yu, P Li, K Wang - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Exosomes are a type of extracellular vesicles (EVs) secreted by almost all cells, with a
diameter range of 30–150 nm and a lipid bilayer membrane. Exosomes are now considered …

Exosomes in the ascites of ovarian cancer patients: origin and effects on anti-tumor immunity

P Peng, Y Yan, S Keng - Oncology reports, 2011 - spandidos-publications.com
This study was performed to identify the origin of the ascites-derived exosomes from patients
with ovarian cancer and to observe the effect of exosomes on anti-tumor immunity …

[HTML][HTML] Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes …

R Alonso, C Mazzeo, MC Rodríguez, M Marsh… - Cell Death & …, 2011 - nature.com
Multivesicular bodies (MVBs) are endocytic compartments that contain intraluminal vesicles
formed by inward budding from the limiting membrane of endosomes. In T lymphocytes …