Selenium, as one of the essential microelements, plays an irreplaceable role in metabolism
regulation and cell survival. Selenium metabolism and regulation have great effects on …

Mercury (Hg) is a persistent heavy metal contaminant with definite hepatotoxicity. Selenium
(Se) has been shown to alleviate liver damage induced by heavy metals. Therefore, the …

Overdose of acetaminophen (paracetamol), a widely used non-prescriptive analgesic and
antipyretic medication, is one of the main causes of drug-induced acute liver failure around …

Acetaminophen, also known as N‐acetyl‐para‐aminophenol (NAPAP), is a traditional
antipyretic and analgesic that is used extensively around the world to treat colds and fevers …

Food colorants are widely used by humans in food production and preparation; however,
their potential toxicity requires an in-depth analysis. In this study, five out of 15 commercial …

Aims: Studies demonstrated that oxidized fish oil (OFO) promoted oxidative stress and
induced mitochondrial dysfunction and lipotoxicity, which attenuated beneficial effects of fish …

Selenium (Se) deficiency significantly impacts the cow breeding industry by reducing the
milk quality of dairy cows and affecting the health of calves. The molecular mechanism of Se …

Acetaminophen (APAP) is one of the most widely used drugs with antipyretic and analgesic
effects, and thus hepatotoxicity from the overdose of APAP becomes one of the most …

Excessive N-acetyl-p-benzoquinone imine (NAPQI) formation is a starting event that triggers
oxidative stress and subsequent hepatocyte necrosis in acetaminophen (APAP) overdose …

Cisplatin is one of the most active chemotherapy drugs to treat solid tumors. However, it also
causes various side effects, especially nephrotoxicity, in which oxidative stress plays critical …