Single‐dose local anesthetics exhibit a type‐, dose‐, and time‐dependent chondrotoxic effect on chondrocytes and cartilage: a systematic review of the current …

PC Kreuz, M Steinwachs… - Knee surgery, sports …, 2018 - Wiley Online Library
Purpose Many studies have shown that local anesthetics may impede chondrocyte
metabolism. However, the influence of a single‐dose local anesthetics is controversial. The …

Chondrotoxicity of intra-articular injection treatment: a scoping review

C Pirri, A Sorbino, N Manocchio, N Pirri… - International Journal of …, 2024 - mdpi.com
The purpose of this scoping review was to identify possible chondrotoxic effects caused by
drugs usually used for intra-articular injections. PubMed, Scopus, Web of Science and …

Efficacy and safety of the pulsed electromagnetic field in osteoarthritis: a meta-analysis

Z Wu, X Ding, G Lei, C Zeng, J Wei, J Li, H Li, T Yang… - BMJ open, 2018 - bmjopen.bmj.com
Objective To investigate the efficacy and safety of the pulsed electromagnetic field (PEMF)
therapy in treating osteoarthritis (OA). Design Meta-analysis. Data sources PubMed …

Dexamethasone and dexmedetomidine as an adjuvant to intraarticular bupivacaine for postoperative pain relief in knee arthroscopic surgery: A randomized trial

SM Moeen, IK Ramadan, HA Elkady - Pain Physician, 2017 - search.proquest.com
BACKGROUND: Knee arthroscopy causes minimal trauma, however, good analgesia is
required for early rehabilitation and return to normal life in the patients. OBJECTIVE: We …

Pain management for orthopedic injuries

N Nischal, E Arulraja… - Emergency Medicine …, 2020 - emed.theclinics.com
Pain is the most common chief complaint in the emergency department (ED), making its
appropriate evaluation and management an important skill for providers to master. 1 …

Analgesic effect and safety of single-dose intra-articular magnesium after arthroscopic surgery: a systematic review and meta-analysis

C Zeng, Y Li, J Wei, D Xie, X Xie, L Li, S Gao, W Luo… - Scientific Reports, 2016 - nature.com
To examine the analgesic effect and safety of single-dose intra-articular (IA) magnesium
(Mg) after arthroscopic surgery. Pubmed, Embase and Cochrane library were searched …

Effect of species, concentration and volume of local anesthetics on intervertebral disk degeneration in rats with discoblock

W Wang, B Xiao, L Yu, H Wang, J Qi, Y Xi… - European Spine …, 2022 - Springer
Purpose Discoblock is effective in relieving discogenic low back pain, but it can also cause
intervertebral disk degeneration (IDD). The effect of species, concentration and volume of …

Intra-articular magnesium plus bupivacaine is the most effective and safe postoperative analgesic option following knee arthroscopy: a network meta-analysis

Y He, H He, X Li, G Lei, D Xie, Y Wang - Arthroscopy: The Journal of …, 2022 - Elsevier
Purpose To evaluate the comparative efficacy and safety of single-dose intra-articular
injection of commonly used analgesics after knee arthroscopy. Methods A systematic …

Influence of ketorolac supplementation on pain control for knee arthroscopy: a meta‐analysis of randomized controlled trials

R Wan, S Liu, Z Kuang, Q Ran, C Zhao… - Orthopaedic …, 2020 - Wiley Online Library
Introduction The efficacy of ketorolac supplementation on pain control for knee arthroscopy
remains controversial. We conduct a systematic review and meta‐analysis to explore the …

Comparison of subacromial injection and interscalene block for immediate pain management after arthroscopic rotator cuff repair

BD Gross, SA Paganessi, O Vazquez - Arthroscopy: The Journal of …, 2020 - Elsevier
Purpose To compare the efficacy of a subacromial injection (SAI) with a single-shot
interscalene block (ISB) for immediate postoperative pain relief after outpatient arthroscopic …