Aggregation of alpha-synuclein (ASYN) in Lewy bodies and Lewy neurites is the typical
pathological hallmark of Parkinson's disease (PD) and other synucleinopathies …

Background/Aims: The study aimed to investigate the protective effect of curcumin against
oxidative stress-induced injury of Parkinson's disease (PD) through the Wnt/β-catenin …

Common neurodegenerative proteinopathies, such as Alzheimer's disease (AD) and
Parkinson's disease (PD), are characterized by the misfolding and aggregation of toxic …

Drosophila melanogaster has contributed significantly to the understanding of disease
mechanisms in Parkinson's disease (PD) as it is one of the very few PD model organisms …

Rodent models and molecular tools, mainly omics and RNA interference, have been
rigorously used to decode the intangible etiology and pathogenesis of Parkinson's disease …

Synphilin-1 is a protein encoded by the human SNCAIP gene whose function has yet to be
fully understood. However, it has been linked to familial Parkinson's disease (PD). Synphilin …

Abstract α-Synuclein is a pleiotropic protein underlying a group of progressive
neurodegenerative diseases, including Parkinson's disease and dementia with Lewy …

Abstract Synphilin-1, a cytoplasmic protein, interacts with α-synuclein which is one of the
main constituents of Lewy bodies and plays an important role in the pathology of Parkinson's …

It has been observed that there is a lower Parkinson's disease (PD) incidence in tobacco
users. Nicotine is a cholinergic agonist and is the principal psychoactive compound in …

Abstract α-synuclein (aSyn) is associated with both sporadic and familial forms of
Parkinson's disease (PD), the second most common neurodegenerative disorder after …