[HTML][HTML] Recent advances in the molecular mechanism of thalidomide teratogenicity

S Gao, S Wang, R Fan, J Hu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Thalidomide was first marketed in 1957 but soon withdrawn because of its notorious
teratogenicity. Studies on the mechanism of action of thalidomide revealed the pleiotropic …

Modeling and characterization of lenalidomide-loaded tripolyphosphate-crosslinked chitosan nanoparticles for anticancer drug delivery

AM Jafari, A Morsali, MR Bozorgmehr… - International Journal of …, 2024 - Elsevier
Tripolyphosphate-crosslinked chitosan (TPPCS) nanoparticles were employed in the
encapsulation of lenalidomide (LND) using a straightforward ionic cross-linking approach …

β-cyclodextrin-lenalidomide anticancer drug delivery nanosystem: A quantum chemical approach

H Harati, A Morsali, MR Bozorgmehr… - Journal of Molecular …, 2021 - Elsevier
Abstract β-cyclodextrin (β-CD) has been widely used as a nanocarrier for anticancer drugs
due to its convenient shape and size. The therapeutic agents can be loaded into the cavity …

[HTML][HTML] Identification of critical molecular factors and side effects underlying the response to thalicthuberine in prostate cancer: a systems biology approach

F Saberi, Z Dehghan, E Noori, Z Taheri… - Avicenna journal of …, 2023 - ncbi.nlm.nih.gov
Background: Uncontrolled mitosis of cancer cells and resistance cells to chemotherapy
drugs are the challenges of prostate cancer. Thalicthuberine causes a mitotic arrest and a …

Thalidomide and its analogs differentially target fibroblast growth factor receptors: thalidomide suppresses FGFR gene expression while pomalidomide dampens …

L Sundaresan, P Kumar, J Manivannan… - Chemical Research …, 2019 - ACS Publications
Thalidomide is an infamous teratogen and it is continuously being explored for its anticancer
properties. Fibroblast growth factor receptors (FGFRs) are implicated in embryo …

Ectopic release of nitric oxide modulates the onset of cardiac development in avian model

P Kumar, A Ghosh, L Sundaresan, P Kathirvel… - In Vitro Cellular & …, 2020 - Springer
Heart development is one of the earliest developmental events, and its pumping action is
directly linked to the intensity of development of other organs. Heart contractions mediate the …

Is the superparamagnetic iron oxide nanoparticle a suitable carrier for the anticancer drug lenalidomide? A quantum chemical approach

M Teymoori, A Morsali, MR Bozorgmehr… - Inorganic Chemistry …, 2021 - inorgchemres.org
The use of superparamagnetic iron oxide nanoparticles (SION) in targeted drug delivery has
become widespread because they can be directed at cancerous tissue by applying an …