Monocytes and Macrophages in COVID-19
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …
pandemic with massive global health and socioeconomic consequences. The disease is …
Virus-induced senescence is a driver and therapeutic target in COVID-19
S Lee, Y Yu, J Trimpert, F Benthani, M Mairhofer… - Nature, 2021 - nature.com
Derailed cytokine and immune cell networks account for the organ damage and the clinical
severity of COVID-19 (refs.,,–). Here we show that SARS-CoV-2, like other viruses, evokes …
severity of COVID-19 (refs.,,–). Here we show that SARS-CoV-2, like other viruses, evokes …
[HTML][HTML] Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy
Detailed knowledge of the molecular biology of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral replication, host …
coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral replication, host …
SARS-CoV-2 disease severity and transmission efficiency is increased for airborne compared to fomite exposure in Syrian hamsters
Transmission of SARS-CoV-2 is driven by contact, fomite, and airborne transmission. The
relative contribution of different transmission routes remains subject to debate. Here, we …
relative contribution of different transmission routes remains subject to debate. Here, we …
SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues …
ME Francis, U Goncin, A Kroeker, C Swan… - PLoS …, 2021 - journals.plos.org
COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) infection is a disease affecting several organ systems. A model that …
syndrome coronavirus 2) infection is a disease affecting several organ systems. A model that …
Ad26. COV2. S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques
M Aid, SJ Vidal, C Piedra-Mora, S Ducat… - PLoS …, 2022 - journals.plos.org
Syrian golden hamsters exhibit features of severe disease after SARS-CoV-2 WA1/2020
challenge and are therefore useful models of COVID-19 pathogenesis and prevention with …
challenge and are therefore useful models of COVID-19 pathogenesis and prevention with …
SARS-CoV-2 in humans
The novel coronavirus SARS-CoV-2 became pandemic at the beginning of 2020, and
caused about 80 million cases and more than 1.8 million deaths by the end of the year. As …
caused about 80 million cases and more than 1.8 million deaths by the end of the year. As …
Ad26. COV2. S Prevents SARS-CoV-2 Induced Pathways of Inflammation and Thrombosis in Hamsters
M Aid, SJ Vidal, C Piedra-Mora, S Ducat, CN Chan… - bioRxiv, 2021 - biorxiv.org
Syrian golden hamsters exhibit features of severe disease after SARS-CoV-2 challenge and
are therefore useful models of COVID-19 pathogenesis and prevention with vaccines …
are therefore useful models of COVID-19 pathogenesis and prevention with vaccines …