Background Individuals affected with autism often suffer additional co-morbidities such as
intellectual disability. The genes contributing to autism cluster on a relatively limited number …

Activity-dependent neuroprotective protein (ADNP) syndrome, also known as Helsmoortel-
Van Der Aa syndrome, is a rare condition, which is diagnosed in children exhibiting signs of …

Abstract How N 6-methyladenosine (m6A), the most abundant mRNA modification,
contributes to primate tissue homeostasis and physiological aging remains elusive. Here …

Background ADNP is essential for embryonic development. As such, de novo ADNP
mutations lead to an intractable autism/intellectual disability syndrome requiring …

Progressive supranuclear palsy (PSP) is a pure tauopathy, implicating davunetide,
enhancing Tau-microtubule interaction, as an ideal drug candidate. However, pooling …

NAP (NAPVSIPQ, drug candidate name, davunetide) is the neuroprotective fragment of
activity‐dependent neuroprotective protein (ADNP). Recent studies identified NAPVSIP as a …

(1) Background: Recently, we showed aberrant nuclear/cytoplasmic boundaries/activity-
dependent neuroprotective protein (ADNP) distribution in ADNP-mutated cells. This …

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a peptide involved in physio-
pathological processes of the eye. It exerts multiple effects directly through activation of its …

Amyotrophic lateral Sclerosis (ALS) is a neurodegenerative disease characterized by
progressive degeneration of motor neurons in the central nervous system. Mutations in the …

Activity-dependent neuroprotective protein (ADNP) is vital for embryonic development and
brain formation. Besides, the upregulated expression of ADNP enhances tumorigenesis in …