Polymer–drug conjugate therapeutics: advances, insights and prospects
Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several
conjugates successfully translated into clinical practice. The conjugation of therapeutic …
conjugates successfully translated into clinical practice. The conjugation of therapeutic …
Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
Poly (ethylene glycol) alternatives in biomedical applications
X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
Sustainable design of structural and functional polymers for a circular economy
B von Vacano, H Mangold… - Angewandte Chemie …, 2023 - Wiley Online Library
To achieve a sustainable circular economy, polymer production must start transitioning to
recycled and biobased feedstock and accomplish CO2 emission neutrality. This is not only …
recycled and biobased feedstock and accomplish CO2 emission neutrality. This is not only …
Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA delivery
SS Nogueira, A Schlegel, K Maxeiner… - ACS Applied Nano …, 2020 - ACS Publications
Polysarcosine (pSar) is a polypeptoid based on the endogenous amino acid sarcosine (N-
methylated glycine), which has previously shown potent stealth properties. Here, lipid …
methylated glycine), which has previously shown potent stealth properties. Here, lipid …
Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …
countless human lives, however, is seriously challenged by the quick emergence of …
Polymeric Nanoparticles for Drug Delivery
MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …
necessitated the creation of more sophisticated drug delivery systems. Polymeric …
Key progresses of MOE key laboratory of macromolecular synthesis and functionalization in 2022
X Deng, K Chen, K Pang, X Liu, M Gao, J Ren… - Chinese Chemical …, 2024 - Elsevier
Abstract In 2022, The MOE Key Laboratory of Macromolecular Synthesis and
Functionalization in Zhejiang University had achieved several important results. First, a …
Functionalization in Zhejiang University had achieved several important results. First, a …
Nanoparticle entry into cells; the cell biology weak link
G Griffiths, J Gruenberg, M Marsh, J Wohlmann… - Advanced Drug Delivery …, 2022 - Elsevier
Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …
[HTML][HTML] Hydrophilic polymers: Current trends and visions for the future
N Bayliss, BVKJ Schmidt - Progress in Polymer Science, 2023 - Elsevier
Hydrophilic polymers are a major class of polymers in polymer science. They are found in
broad range of applications from superabsorbers to drug-delivery. In recent years, a plethora …
broad range of applications from superabsorbers to drug-delivery. In recent years, a plethora …