Reward processing and mood-related symptoms: An RDoC and translational neuroscience perspective

R Nusslock, LB Alloy - Journal of affective disorders, 2017 - Elsevier
Background Two objectives of the NIMH Research Domain Criteria (RDoC) initiative are to
identify (a) mechanisms that are common to multiple psychiatric disorders, and (b) …

A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitry and a road map for future research

ML Phillips, HA Swartz - American Journal of Psychiatry, 2014 - Am Psychiatric Assoc
Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …

Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum

D Watson, HF Levin‐Aspenson, MA Waszczuk… - World …, 2022 - Wiley Online Library
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological
system that addresses shortcomings of traditional mental disorder diagnoses, including …

Role of reward sensitivity and processing in major depressive and bipolar spectrum disorders

LB Alloy, T Olino, RD Freed, R Nusslock - Behavior therapy, 2016 - Elsevier
Abstract Since Costello's (1972) seminal Behavior Therapy article on loss of reinforcers or
reinforcer effectiveness in depression, the role of reward sensitivity and processing in both …

Connectomics of bipolar disorder: a critical review, and evidence for dynamic instabilities within interoceptive networks

A Perry, G Roberts, PB Mitchell, M Breakspear - Molecular psychiatry, 2019 - nature.com
The notion that specific cognitive and emotional processes arise from functionally distinct
brain regions has lately shifted toward a connectivity-based approach that emphasizes the …

The development and course of bipolar spectrum disorders: An integrated reward and circadian rhythm dysregulation model

LB Alloy, R Nusslock, EM Boland - Annual review of clinical …, 2015 - annualreviews.org
In this article, we present and review the evidence for two major biopsychosocial theories of
the onset and course of bipolar spectrum disorders (BSDs) that integrate behavioral …

Dissociable patterns of abnormal frontal cortical activation during anticipation of an uncertain reward or loss in bipolar versus major depression

HW Chase, R Nusslock, JRC Almeida… - Bipolar …, 2013 - Wiley Online Library
Objectives Recent research has found abnormalities in reward‐related neural activation in
bipolar disorder (BD), during both manic and euthymic phases. However, reward‐related …

Regulatory behavior and frontal activity: Considering the role of revised‐BIS in relative right frontal asymmetry

PA Gable, LB Neal, AH Threadgill - Psychophysiology, 2018 - Wiley Online Library
Essential to human behavior are three core personality systems: approach, avoidance, and
a regulatory system governing the two motivational systems. Decades of research has linked …

Asymmetrical frontal cortical activity associated with differential risk for mood and anxiety disorder symptoms: An RDoC perspective

R Nusslock, K Walden, E Harmon-Jones - International Journal of …, 2015 - Elsevier
The recently launched NIMH Research Domain Criteria (RDoC) initiative aims to examine
the relationship between core biobehavioral dimensions and symptom profiles that either cut …

The corpus callosum: a commissural road to anger and aggression

DJLG Schutter, E Harmon-Jones - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
According to the frontal cortical asymmetry model of motivational direction, anger and
aggression are associated with approach motivation and a dominant left frontal hemisphere …