Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke

JL Fan, RC Nogueira, P Brassard… - Journal of Cerebral …, 2022 - journals.sagepub.com
Restoring perfusion to ischemic tissue is the primary goal of acute ischemic stroke care, yet
only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is …

[HTML][HTML] Implications of post-recanalization perfusion deficit after acute ischemic stroke: a scoping review of clinical and preclinical imaging studies

N van der Knaap, BAA Franx, CBLM Majoie… - Translational Stroke …, 2024 - Springer
The goal of reperfusion therapy for acute ischemic stroke (AIS) is to restore cerebral blood
flow through recanalization of the occluded vessel. Unfortunately, successful recanalization …

The effect of hypercapnia on the directional sensitivity of dynamic cerebral autoregulation and the influence of age and sex

RB Panerai, A Davies, RH Clough… - Journal of Cerebral …, 2024 - journals.sagepub.com
The cerebral circulation responds differently to increases in mean arterial pressure (MAP),
compared to reductions in MAP. We tested the hypothesis that this directional sensitivity is …

Lower middle cerebral artery blood velocity during low-volume high-intensity interval exercise in chronic stroke

AA Whitaker, S Waghmare… - Journal of Cerebral …, 2024 - journals.sagepub.com
High-intensity interval training (HIIE) may present unique challenges to the cerebrovascular
system in individuals post-stroke. We hypothesized lower middle cerebral artery blood …

Intermittent hypoxia protects against hypoxic-ischemic brain damage by inducing functional angiogenesis

Y Guan, Y Gu, H Shao, W Ma, G Li… - Journal of Cerebral …, 2023 - journals.sagepub.com
Ischemic stroke (IS) induces neurological damage due to cerebrovascular occlusion.
Restoring blood perfusion to the ischemic brain area in a timely fashion is the most effective …

Hyperoside ameliorates cerebral ischaemic–reperfusion injury by opening the TRPV4 channel in vivo through the IP3-PKC signalling pathway

L Shi, C Jiang, H Xu, J Wu, J Lu, Y He, X Yin… - Pharmaceutical …, 2023 - Taylor & Francis
Abstract Context Hyperoside (Hyp), one of the active flavones from Rhododendron
(Ericaceae), has beneficial effects against cerebrovascular disease. However, the effect of …

Effectiveness of butylphthalide on cerebral autoregulation in ischemic stroke patients with large artery atherosclerosis (EBCAS study): A randomized, controlled …

ZN Guo, BH Yue, L Fan, J Liu, Y Zhu… - Journal of Cerebral …, 2023 - journals.sagepub.com
Finding appropriate drugs to improve cerebral autoregulation (CA) in patients with acute
ischemic stroke (AIS) is necessary to improve prognosis. We aimed to investigate the effect …

Association Between Long‐Term Exposure to Fine Particulate Matter Constituents and Progression of Cerebral Blood Flow Velocity in Beijing: Modifying Effect of …

Z Xu, Z Han, J Wang, R Jin, Z Li, Z Wu, Z Zhao… - …, 2023 - Wiley Online Library
Few studies have explored the effects of fine particulate matter (PM2. 5) and its constituents
on the progression of cerebral blood flow velocity (BFV) and the potential modifying role of …

What are the effects of acute exercise and exercise training on cerebrovascular hemodynamics following stroke? A systematic review and meta-analysis

K Moncion, EY Allison, BK Al-Khazraji… - Journal of Applied …, 2022 - journals.physiology.org
Limited data exist regarding the effects of acute exercise and exercise training on
cerebrovascular hemodynamic variables after stroke. This systematic review and meta …

Effect of drug interventions on cerebral hemodynamics in ischemic stroke patients

O Llwyd, JL Fan, M Müller - Journal of Cerebral Blood Flow & …, 2022 - journals.sagepub.com
The ischemic penumbra is sensitive to alterations in cerebral perfusion. A myriad of drugs
are used in acute ischemic stroke (AIS) management, yet their impact on cerebral …