Process Development for the First GMP Synthesis of SGD-9501-TFA, Part 2: Synthesis of the Payload, Linker, and Drug Linker

K Payne, JC Tran, B Gill, W Guy… - … Process Research & …, 2024 - ACS Publications
The discovery of novel auristatin-derived antibody drug conjugates (ADCs) with attenuated
bystander activity is an area of intense research. Recently, drug-linker SGD-9501-TFA …