Understanding the broad influence of sex hormones and sex differences in the brain

BS McEwen, TA Milner - Journal of neuroscience research, 2017 - Wiley Online Library
Sex hormones act throughout the entire brain of both males and females via both genomic
and nongenomic receptors. Sex hormones can act through many cellular and molecular …

Oestradiol as a neuromodulator of learning and memory

LR Taxier, KS Gross, KM Frick - Nature Reviews Neuroscience, 2020 - nature.com
Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …

[HTML][HTML] Sex hormones affect neurotransmitters and shape the adult female brain during hormonal transition periods

C Barth, A Villringer, J Sacher - Frontiers in neuroscience, 2015 - frontiersin.org
Sex hormones have been implicated in neurite outgrowth, synaptogenesis, dendritic
branching, myelination and other important mechanisms of neural plasticity. Here we review …

Estrogen effects on cognitive and synaptic health over the lifecourse

Y Hara, EM Waters, BS McEwen… - Physiological …, 2015 - journals.physiology.org
Estrogen facilitates higher cognitive functions by exerting effects on brain regions such as
the prefrontal cortex and hippocampus. Estrogen induces spinogenesis and synaptogenesis …

Sex differences in the brain: Implications for behavioral and biomedical research

E Choleris, LAM Galea, F Sohrabji, KM Frick - … & Biobehavioral Reviews, 2018 - Elsevier
Biological differences between males and females are found at multiple levels. However,
females have too often been under-represented in behavioral neuroscience research, which …

Structural plasticity upon learning: regulation and functions

P Caroni, F Donato, D Muller - Nature Reviews Neuroscience, 2012 - nature.com
Recent studies have provided long-sought evidence that behavioural learning involves
specific synapse gain and elimination processes, which lead to memory traces that influence …

[HTML][HTML] Structural plasticity of the hippocampus in response to estrogens in female rodents

PAS Sheppard, E Choleris, LAM Galea - Molecular brain, 2019 - Springer
It is well established that estrogens affect neuroplasticity in a number of brain regions. In
particular, estrogens modulate and mediate spine and synapse formation as well as …

Estrogens and phytoestrogens in body functions

I Ceccarelli, L Bioletti, S Peparini, E Solomita… - Neuroscience & …, 2022 - Elsevier
Estrogens are the hormones of reproduction in women as well as of many other important
functions in the male and female body. They undergo significant changes in the different …

[HTML][HTML] 17β-Estradiol acutely potentiates glutamatergic synaptic transmission in the hippocampus through distinct mechanisms in males and females

JG Oberlander, CS Woolley - The Journal of neuroscience, 2016 - ncbi.nlm.nih.gov
Estradiol (E2) acutely potentiates glutamatergic synaptic transmission in the hippocampus of
both male and female rats. Here, we investigated whether E2-induced synaptic potentiation …

Sex steroid hormones matter for learning and memory: estrogenic regulation of hippocampal function in male and female rodents

KM Frick, J Kim, JJ Tuscher, AM Fortress - Learning & Memory, 2015 - learnmem.cshlp.org
Ample evidence has demonstrated that sex steroid hormones, such as the potent estrogen
17β-estradiol (E2), affect hippocampal morphology, plasticity, and memory in male and …