Depression is a prevalent, complex, and highly debilitating disease. The full comprehension
of this disease is still a global challenge. Indeed, relapse, recurrency, and therapeutic …

Background Perioperative neurocognitive disorders (PND) with a high incidence frequently
occur in elderly surgical patients closely associated with prolonged anesthesia-induced …

Treatment of anxiety and depression predominantly centres around pharmacological
interventions, which have faced criticism for their associated side effects, lack of efficacy and …

Background: Multiple sclerosis (MS) is characterized by a combination of inflammatory and
demyelination processes in the spinal cord and brain. Conventional drugs generally target …

Depression is a highly prevalent psychological disorder characterized by persistent
dysphoria, psychomotor retardation, insomnia, anhedonia, suicidal ideation, and a …

Background Clinical and animal studies demonstrated that neuroinflammation from
anesthesia (sevoflurane) is the main contributor to cause perioperative neurocognitive …

Secondary degeneration is defined as a set of destructive events that damage cells and
structures that were initially spared or only peripherally affected by the primary insult …

Background: Inflammation is considered to be a link between diabetes and central nervous
system (CNS) disorders, including depression and anxiety. Metformin is suggested to have …

Growing evidence indicates that neuroinflammation plays a critical role in anxiety,
depression, and cognitive impairment. Sleep loss disrupts the host's immune balance and …

It has been consistently found that exposure to ambient air pollution, such as particulate
matter (PM), results in cognitive impairments and mental disorders. This study aimed to …