The role of obesity-induced perivascular adipose tissue (PVAT) dysfunction in vascular homeostasis

A Stanek, K Brożyna-Tkaczyk, W Myśliński - Nutrients, 2021 - mdpi.com
Perivascular adipose tissue (PVAT) is an additional special type of adipose tissue
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …

Maternal obesity and the impact of associated early-life inflammation on long-term health of offspring

M Denizli, ML Capitano, KL Kua - Frontiers in cellular and infection …, 2022 - frontiersin.org
The prevalence of obesity is increasingly common in the United States, with~ 25% of women
of reproductive age being overweight or obese. Metaflammation, a chronic low grade …

Sex-specific effects of a high fat diet on aortic inflammation and dysfunction

V Tran, H Brettle, H Diep, QN Dinh, M O'Keeffe… - Scientific Reports, 2023 - nature.com
Obesity and vascular dysfunction are independent and sexually dimorphic risk factors for
cardiovascular disease. A high fat diet (HFD) is often used to model obesity in mice, but the …

Suppressed vascular Rho-kinase activation is a protective cardiovascular mechanism in obese female mice

GS Barbosa, RM Costa, W Awata, S Singh… - Bioscience …, 2023 - portlandpress.com
Background: Obesity is the number one cardiovascular risk factor for both men and women
and is a complex condition. Although a sex dimorphism on vascular function has already …

Cross-talks between perivascular adipose tissue and neighbors: Multifaceted nature of nereids

Y Li, Z Chen, Y Xiao, X Li - Frontiers in Pharmacology, 2024 - frontiersin.org
Perivascular adipose tissue (PVAT) is a unique fat depot surrounding blood vessels and
plays a vital role in the progression of vascular remodeling and dysfunction. PVAT exhibits …

Ethanol consumption favors pro-contractile phenotype of perivascular adipose tissue: A role for interleukin-6

JA Simplicio, TMH Dourado, WMC Awata, GT do Vale… - Life Sciences, 2023 - Elsevier
Perivascular adipose tissue (PVAT) exerts anticontractile effect, but under non-physiological
conditions it may contribute to vascular dysfunction by releasing pro-inflammatory cytokines …

HRD1 reduction promotes cholesterol-induced vascular smooth muscle cell phenotypic change via endoplasmic reticulum stress

L Wang, Z Ren, L Wu, X Zhang, M Wang, H Niu… - Molecular and Cellular …, 2024 - Springer
Phenotypic change of vascular smooth muscle cells (VSMCs) is the main contributor of
vascular pathological remodeling in atherosclerosis. The endoplasmic reticulum (ER) is …

Nutritional Composition and Effect of Loquat Fruit (Eriobotrya japonica L. var. Navela) on Lipid Metabolism and Liver Steatosis in High-Fat High-Sucrose Diet-Fed …

I Mokhtari, M Moumou, C Mokhtari… - … nutrition and food …, 2024 - pmc.ncbi.nlm.nih.gov
Loquat (Eriobotrya japonica L.) is a popular fruit known for its sweet and slightly tangy flavor,
which is widely consumed both fresh and in various processed forms. This study aimed to …

Insights by which TUDCA is a potential therapy against adiposity

IN Freitas, JA da Silva Jr, KM Oliveira… - Frontiers in …, 2023 - frontiersin.org
Adipose tissue is an organ with metabolic and endocrine activity. White, brown and ectopic
adipose tissues have different structure, location, and function. Adipose tissue regulates …

Dahl Salt-Resistant Rat Is Protected against Hypertension during Diet-Induced Obesity

S Lee, S Jang, JY Kim, I Kim - Nutrients, 2022 - mdpi.com
A high-fat diet (HFD) frequently causes obesity-induced hypertension. Because Dahl salt-
resistant rats are protected against hypertension after high-salt or high-fructose intake, it is of …