In the presence of glucose, yeast undergoes an important remodelling of its metabolism.
There are changes in the concentration of intracellular metabolites and in the stability of …

Transport across the plasma membrane is the first step at which nutrient supply is tightly
regulated in response to intracellular needs and often also rapidly changing external …

The pathogenic yeast Candida albicans is both a powerful commensal and a pathogen of
humans that can infect wide range of organs and body sites. Metabolic flexibility promotes …

The yeast Rgt1 repressor inhibits transcription of the glucose transporter (HXT) genes in the
absence of glucose. It does so by recruiting the general corepressor complex Ssn6-Tup1 …

We identified in the methylotrophic yeast Hansenula polymorpha (syn. Pichia angusta) a
novel hexose transporter homologue gene, HXS1 (hex ose s ensor), involved in …

The milk yeast Kluyveromyces lactis degrades glucose through glycolysis and the pentose
phosphate pathway and follows a mainly respiratory metabolism. Here, we investigated the …

In the respiratory yeast Kluyveromyces lactis, little is known about the factors regulating the
metabolic response to oxygen shortage. After searching for homologues of characterized …

Low oxygen adaptation is essential for aerobic fungi that must survive in varied oxygen
environments. Pathogenic fungi in particular must adapt to the low oxygen host tissue …

Kluyveromyces lactis strains impaired in the nonhomologous end-joining pathway are
relevant tools for the homologous integration of exogenous DNA into the genome, as in the …

Sensing of extracellular glucose is necessary for cells to adapt to glucose variation in their
environment. In the respiratory yeast Kluyveromyces lactis, extracellular glucose controls the …