ABSTRACT P2 is the original member of a highly successful family of temperate phages that
are frequently found in the genomes of gram-negative bacteria. This article focuses on the …

Antisense transcription has been extensively recognized as a regulatory mechanism for
gene expression across all kingdoms of life. Despite the broad importance and extensive …

Plague is an endemic infectious disease caused by Yersinia pestis. In this study, we isolated
fourteen phages with similar sequence arrangements to phage 186; these phages exhibited …

Engineered phage with properties optimised for the treatment of bacterial infections hold
great promise, but require careful characterisation by a number of approaches. Phage …

The CII protein of temperate coliphage 186, like the unrelated CII protein of phage λ, is a
transcriptional activator that primes expression of the CI immunity repressor and is critical for …

Convergent promoters exert transcriptional interference (TI) by several mechanisms
including promoter occlusion, where elongating RNA polymerases (RNAP s) block access to …

Bacteriophages (phage) are considered a primary resource for developing new therapeutic
treatments for bacterial infections. Phage will likely be used either as an alternatives to …

Microorganisms inhabit every extreme location of our planet. In their journey through the
ages, they have been able to incredibly adapt to a myriad of different environmental …