Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …
with water between the wraps. The measurement of damage to the myelin sheaths, the …
Quantitative assessment of myelin density using [11C]MeDAS PET in patients with multiple sclerosis: a first-in-human study
CWJ van der Weijden, JF Meilof… - European journal of …, 2022 - Springer
Purpose Multiple sclerosis (MS) is a disease characterized by inflammatory demyelinated
lesions. New treatment strategies are being developed to stimulate myelin repair …
lesions. New treatment strategies are being developed to stimulate myelin repair …
Diffusion-derived parameters in lesions, peri-lesion and normal-appearing white matter in multiple sclerosis using tensor, kurtosis and fixel-based analysis
CWJ van der Weijden… - Journal of Cerebral …, 2022 - journals.sagepub.com
Neuronal damage is the primary cause of long-term disability of multiple sclerosis (MS)
patients. Assessment of axonal integrity from diffusion MRI parameters might enable better …
patients. Assessment of axonal integrity from diffusion MRI parameters might enable better …
[HTML][HTML] Investigation of image-derived input functions for non-invasive quantification of myelin density using [11C] MeDAS PET
CWJ van der Weijden, A van der Hoorn, Y Wang… - Neuroimage, 2022 - Elsevier
Multiple sclerosis (MS) is an inflammatory demyelinating disease. Current treatments are
focussed on immune suppression to modulate pathogenic activity that causes myelin …
focussed on immune suppression to modulate pathogenic activity that causes myelin …
Myelin Imaging of the Spinal Cord in Animal Models and Patients with Multiple Sclerosis Using [11C] MeDAS PET: A Translational Study
CWJ van der Weijden, AKMA Ahmed… - Journal of Nuclear …, 2024 - jnm.snmjournals.org
Multiple sclerosis (MS) is a neurodegenerative disease characterized by demyelinated
lesions in the brain and spinal cord. A few clinical studies using PET to image myelin in the …
lesions in the brain and spinal cord. A few clinical studies using PET to image myelin in the …
[PDF][PDF] MODELS OF FOCAL NEUROINFLAMMATION
S Vainio - researchgate.net
Neuroinflammation (NI) is a key player in neurodegenerative diseases, such as multiple
sclerosis (MS). Magnetic resonance imaging is the gold standard imaging method for …
sclerosis (MS). Magnetic resonance imaging is the gold standard imaging method for …
[PDF][PDF] Current Radiotracers for PET Imaging of Multiple Sclerosis
A Athreya, C Taswell - brainhealthalliance.org
CD4+ and CD8+ cells secrete IL-17 and chemokine uptake increases, causing Th17 cells to
migrate into the CSF and perivascular spaces. Th17 cells increase the permeability of the …
migrate into the CSF and perivascular spaces. Th17 cells increase the permeability of the …