The mammary gland undergoes a spectacular series of changes as it develops, and
maintains a remarkable capacity to remodel and regenerate for several decades. Mammary …

Embryogenesis is a highly complex and dynamic process, and its visualization is crucial for
understanding basic physiological processes during development and for identifying and …

The heart is the first functioning organ to form during development. During gastrulation, the
cardiac progenitors reside in the lateral plate mesoderm but maintain close contact with the …

During its earliest stages, the avian embryo is approximately planar. Through a complex
series of folds, this flat geometry is transformed into the intricate three-dimensional structure …

Application of optical imaging in developmental biology marks an exciting frontier in
biomedical optics. Optical resolution and imaging depth allow for investigation of growing …

The chick embryo has long been a favorite model system for morphologic and physiologic
studies of the developing heart, largely because of its easy visualization and amenability to …

The transformation of the straight embryonic heart tube into a helically wound loop is named
cardiac looping. Such looping is regarded as an essential process in cardiac …

During developmental stages, biomechanical stimuli on cardiac cells modulate genetic
programs, and deviations from normal stimuli can lead to cardiac defects. Therefore, it is …

Despite extensive study, the morphogenetic mechanisms of heart looping remain
controversial because of a lack of information concerning precise tissue-level deformation …

High temporal resolution OCT imaging is very advantageous for analyzing cardiac
mechanics in the developing embryonic heart of small animals. An image-based …