[HTML][HTML] Emerging role of ferroptosis in diabetic kidney disease: molecular mechanisms and therapeutic opportunities

H Wang, D Liu, B Zheng, Y Yang, Y Qiao… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Diabetic kidney disease (DKD) is one of the most common and severe microvascular
complications of diabetes mellitus (DM), and has become the leading cause of end-stage …

Antioxidant, anti-inflammatory, and metabolic properties of tocopherols and tocotrienols: clinical implications for vitamin E supplementation in diabetic kidney disease

A Di Vincenzo, C Tana, H El Hadi, C Pagano… - International Journal of …, 2019 - mdpi.com
Diabetes mellitus is a metabolic disorder characterized by the development of vascular
complications associated with high morbidity and mortality and the consequent relevant …

Protein kinase C: A potential therapeutic target for endothelial dysfunction in diabetes

Q Xiao, D Wang, D Li, J Huang, F Ma, H Zhang… - Journal of Diabetes and …, 2023 - Elsevier
Protein kinase C (PKC) is a family of serine/threonine protein kinases that play an important
role in many organs and systems and whose activation contributes significantly to …

High dose vitamin E attenuates diabetic nephropathy via alleviation of autophagic stress

Y Zhao, W Zhang, Q Jia, Z Feng, J Guo, X Han… - Frontiers in …, 2019 - frontiersin.org
It has been reported that autophagic stress, which is involved in many diseases, plays a key
role in the development of diabetic nephropathy (DN). In this study, we investigated the …

Vitamin E acetate as linactant in the pathophysiology of EVALI

H Lee - Medical hypotheses, 2020 - Elsevier
The recent identification of Vitamin E acetate as one of the causal agents for the e-cigarette,
or vaping, product use associated lung injury (EVALI) is a major milestone. In membrane …

[HTML][HTML] Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis

BM Lane, M Chryst-Stangl, G Wu, M Shalaby… - JCI insight, 2022 - ncbi.nlm.nih.gov
We performed next-generation sequencing in patients with familial steroid-sensitive
nephrotic syndrome (SSNS) and identified a homozygous segregating variant (p. H310Y) in …

[HTML][HTML] Renoprotective effect of N-acetylcystein and vitamin E in bisphenol A-induced rat nephrotoxicity; Modulators of Nrf2/NF-κB and ROS signaling pathway

E Abdelrazik, HM Hassan, Z Abdallah… - Acta Bio Medica …, 2022 - ncbi.nlm.nih.gov
Research design and Methods: Forty-two adult male rats were divided into 7 groups: control,
BPA, NAC, vitamin E, BPA plus NAC, BPA plus vitamin E, and combined BPA, NAC and …

Vitamin E functions by association with a novel binding site on the 67 kDa laminin receptor activating diacylglycerol kinase

D Hayashi, VD Mouchlis, S Okamoto, T Namba… - The Journal of nutritional …, 2022 - Elsevier
It is generally recognized that the main function of α-tocopherol (αToc), which is the most
active form of vitamin E, is its antioxidant effect, while non-antioxidant effects have also been …

The mechanisms of ameliorating effect of a green tea polyphenol on diabetic nephropathy based on diacylglycerol kinase α

D Hayashi, L Wang, S Ueda, M Yamanoue… - Scientific Reports, 2020 - nature.com
Significant efforts have been made to ameliorate diabetic nephropathy (DN) by inhibiting
protein kinase C. However, these efforts have not been successful in human trials …

[PDF][PDF] The Role of Dietary Antioxidants on Oxidative Stress in Diabetic Nephropathy.

FG Yanowsky-Escatell, J Andrade-Sierra… - Iranian journal of …, 2020 - researchgate.net
The Role of Dietary Antioxidants on Oxidative Stress in Diabetic Nephropathy Page 1 KIDNEY
DISEASES 81 R eview Iranian Journal of Kidney Diseases | Volume 14 | Number 2 | March …