Importance Subclinical hypothyroidism, defined as an elevated serum thyrotropin (often
referred to as thyroid-stimulating hormone, or TSH) level with normal levels of free thyroxine …

Context: Although both overt hyper-and hypothyroidism are known to lead to cognitive
impairment, data on the association between subclinical thyroid dysfunction and cognitive …

Importance In clinical guidelines, overt and subclinical thyroid dysfunction are mentioned as
causal and treatable factors for cognitive decline. However, the scientific literature on these …

Context The COVID-19 pandemic continues to exert an immense burden on global health
services. Moreover, up to 63% of patients experience persistent symptoms, including fatigue …

Background The identification of modifiable risk factors for Alzheimer's disease is paramount
for early prevention and the targeting of new interventions. We aimed to assess the …

Subclinical hypothyroidism, which is defined as a thyroid-stimulating hormone concentration
higher than the reference range (generally 4· 5 mIU/L or higher) with normal free thyroxine …

Thyroid hormones (TH) have a cardinal role in the development of the central nervous
system during embryogenesis and early infancy. However, the TH-responsive genes in the …

Increasing evidences supported that subjective cognitive decline (SCD) might be a potential
first symptomatic manifestation of Alzheimer's disease (AD). The rapidly growing number of …

Imbalances in thyroid hormones have been linked with Alzheimer's dementia. Several
studies have reported an association between thyroid disorders, such as hyper-or …

Subclinical hypothyroidism (SCH) is diagnosed when serum thyroid stimulation hormone
(thyrotropin; TSH) levels are above the reference range, accompanied by levels of free …