Secondary metabolism in cannabis
IJ Flores-Sanchez, R Verpoorte - Phytochemistry reviews, 2008 - Springer
Cannabis sativa L. is an annual dioecious plant from Central Asia. Cannabinoids,
flavonoids, stilbenoids, terpenoids, alkaloids and lignans are some of the secondary …
flavonoids, stilbenoids, terpenoids, alkaloids and lignans are some of the secondary …
The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia
JC Fruchart, F Sacks, MP Hermans, G Assmann… - The American journal of …, 2008 - Elsevier
Despite achieving targets for low-density lipoprotein (LDL) cholesterol, blood pressure, and
glycemia in accordance with current standards of care, patients with dyslipidemia remain at …
glycemia in accordance with current standards of care, patients with dyslipidemia remain at …
Cytotoxic edema: mechanisms of pathological cell swelling
D Liang, S Bhatta, V Gerzanich, JM Simard - Neurosurgical focus, 2007 - thejns.org
✓ Cerebral edema is caused by a variety of pathological conditions that affect the brain. It is
associated with two separate pathophysiological processes with distinct molecular and …
associated with two separate pathophysiological processes with distinct molecular and …
Treatment modalities of obesity: what fits whom?
V Hainer, H Toplak, A Mitrakou - Diabetes care, 2008 - Am Diabetes Assoc
The prevalence of obesity is increasing in both developed and developing countries, with
rates reaching∼ 10–35% among adults in the Euro-American region. Obesity is associated …
rates reaching∼ 10–35% among adults in the Euro-American region. Obesity is associated …
Aryl radical activation of C–O bonds: copper-catalyzed deoxygenative difluoromethylation of alcohols
Given their ubiquity in natural products and pharmaceuticals, alcohols represent one of the
most attractive starting materials for the construction of C–C bonds. We report herein the first …
most attractive starting materials for the construction of C–C bonds. We report herein the first …
The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in dyslipidaemic patients
JC Fruchart, FM Sacks, MP Hermans… - Diabetes and …, 2008 - journals.sagepub.com
Despite current standards of care aimed at achieving targets for low-density lipoprotein
(LDL) cholesterol, blood pressure and glycaemia, dyslipidaemic patients remain at high …
(LDL) cholesterol, blood pressure and glycaemia, dyslipidaemic patients remain at high …
In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs
RA Thompson, EM Isin, Y Li, L Weidolf… - Chemical research in …, 2012 - ACS Publications
Idiosyncratic adverse drug reactions (IADRs) in humans can result in a broad range of
clinically significant toxicities leading to attrition during drug development as well as …
clinically significant toxicities leading to attrition during drug development as well as …
Effect of obesity on high‐density lipoprotein metabolism
S Rashid, J Genest - Obesity, 2007 - Wiley Online Library
Reduced levels of high‐density lipoproteins (HDL) in non‐obese and obese states are
associated with increased risk for the development of coronary artery disease. Therefore, it …
associated with increased risk for the development of coronary artery disease. Therefore, it …
Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis
DR Janero, A Makriyannis - Expert opinion on emerging drugs, 2009 - Taylor & Francis
The endogenous cannabinoid (CB)(endocannabinoid) signaling system is involved in a
variety of (patho) physiological processes, primarily by virtue of natural, arachidonic acid …
variety of (patho) physiological processes, primarily by virtue of natural, arachidonic acid …
Diabesity: therapeutic options
S Colagiuri - Diabetes, obesity and metabolism, 2010 - Wiley Online Library
A pathogenic relationship exists between type 2 diabetes and obesity. Over the last decade,
the escalation in diabetes cases has paralleled the rapid increase in obesity rates …
the escalation in diabetes cases has paralleled the rapid increase in obesity rates …