[HTML][HTML] Oxidative stress, innate immunity, and age-related macular degeneration

PX Shaw, T Stiles, C Douglas, D Ho, W Fan… - AIMS molecular …, 2016 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is a leading cause of vision loss affecting tens of
millions of elderly worldwide. Early AMD is characterized by the appearance of soft drusen …

Hypoxia and oxidative stress in the causation of diabetic retinopathy

G B. Arden, S Sivaprasad - Current diabetes reviews, 2011 - benthamdirect.com
Diabetic retinopathy is associated with hyperglycemia, and there is convincing evidence that
oxidative stress (the overproduction of reactive oxygen species (ROS)) measured indirectly …

Association between the vascular endothelial growth factor single nucleotide polymorphisms and diabetic retinopathy risk: A meta‐analysis: 关于血管内皮生长因子单 …

XJ Xie, YM Yang, JK Jiang, YQ Lu - Journal of Diabetes, 2017 - Wiley Online Library
背景这项研究的目的是揭示血管内皮生长因子(vascular endothelial growth factor, VEGF)
单核苷酸多态性(single nucleotide polymorphisms, SNPs) 和糖尿病视网膜病变(diabetes …

Mediators of ocular angiogenesis

Y Qazi, S Maddula, BK Ambati - Journal of genetics, 2009 - Springer
Angiogenesis is the formation of new blood vessels from pre-existing vasculature.
Pathologic angiogenesis in the eye can lead to severe visual impairment. In our review, we …

Genome-wide association study of diabetic retinopathy in a Taiwanese population

YC Huang, JM Lin, HJ Lin, CC Chen, SY Chen… - Ophthalmology, 2011 - Elsevier
PURPOSE:: Diabetic retinopathy (DR) is a microvascular complication of diabetes with a
complex multifactorial pathogenesis. The aim of this study was to identify the susceptibility …

Intravitreous vascular endothelial growth factor and hypoxia-inducible factor 1a in patients with proliferative diabetic retinopathy

X Wang, G Wang, Y Wang - American journal of ophthalmology, 2009 - Elsevier
PURPOSE: To determine vascular endothelial growth factor (VEGF) and hypoxia-inducible
factor 1a (HIF-1a) in the vitreous fluid of patients with proliferative diabetic retinopathy …

Challenges in elucidating the genetics of diabetic retinopathy

JZ Kuo, TY Wong, JI Rotter - JAMA ophthalmology, 2014 - jamanetwork.com
Importance In the past decade, significant progress in genomic medicine and technologic
developments has revolutionized our approach to common complex disorders in many …

The role of genetics in susceptibility to diabetic retinopathy

G Liew, R Klein, TY Wong - International ophthalmology clinics, 2009 - journals.lww.com
Diabetic retinopathy remains the leading cause of blindness in working-aged adults. 1 Over
4 million adults 40 years and older in the United States are estimated to have diabetic …

The pathogenesis of early retinal changes of diabetic retinopathy

GB Arden, S Sivaprasad - Documenta Ophthalmologica, 2012 - Springer
Recent successful trials of antibodies to vascular endothelial growth factor (VEGF) in
diabetic retinopathy implicate this cytokine as a major cause of diabetic retinopathy (DR) …

Do genomic factors play a role in diabetic retinopathy?

AP Cabrera, F Monickaraj, S Rangasamy… - Journal of clinical …, 2020 - mdpi.com
Although there is strong clinical evidence that the control of blood glucose, blood pressure,
and lipid level can prevent and slow down the progression of diabetic retinopathy (DR) as …