The cumulative science linking stress to negative health outcomes is vast. Stress can affect
health directly, through autonomic and neuroendocrine responses, but also indirectly …

As humans age, the risk and severity of infections vary in line with immune competence
according to how the immune system develops, matures, and declines. Several factors …

Importance Few risk factors for long-lasting (≥ 4 weeks) COVID-19 symptoms have been
identified. Objective To determine whether high levels of psychological distress before …

The kynurenine pathway (KP) plays a critical role in generating cellular energy in the form of
nicotinamide adenine dinucleotide (NAD+). Because energy requirements are substantially …

John Dewey was a pragmatist, progressivist, educator, philosopher, and social reformer
(Gutek, 2014). Dewey's various roles greatly impacted education and he was perhaps one of …

Abstract Background About 83,000 COVID-19 patients were confirmed in China up to May
2020. Amid the well-documented threats to physical health, the effects of this public health …

Our group has proposed that in contrast to chronic stress that can have harmful effects, the
short-term (fight-or-flight) stress response (lasting for minutes to hours) is nature's …

Close and caring relationships are undeniably linked to health and well-being at all stages
in the life span. Yet the specific pathways through which close relationships promote optimal …

Chronic psychosocial stress increases disease risk and mortality, but the underlying
mechanisms remain largely unclear. Here we outline an energy-based model for the …

Aging is the greatest risk factor for nearly all major chronic diseases, including
cardiovascular diseases, cancer, Alzheimer's and other neurodegenerative diseases of …