Circumvention of cancer drug resistance is one of the major investigations in nanomedicine.
In this regard, nanotechnology-based drug delivery has offered various implications …

To protect tissues and the organism from disease, potentially harmful cells are removed
through programmed cell death processes, including apoptosis and necroptosis. These …

Tumor necrosis factor-related apoptosis-inducing ligand or Apo 2 ligand (TRAIL/Apo2L) is a
member of the tumor necrosis factor (TNF) family of ligands capable of initiating apoptosis …

Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and
pathological conditions. Resistance to apoptosis is a hallmark of virtually all malignancies …

Melanoma is the most aggressive skin cancer in humans that often expresses MHC class II
(MHC II) molecules, which could make these tumors eliminable by the immune system …

Apoptosis dysregulation is an important mechanism responsible for the intrinsic and
acquired resistance of melanoma, which necessitates the exploration of oncological …

Human serum albumin (HSA) nanoparticles (NPs) surface modified with tumor necrosis
factor (TNF)-related apoptosis-inducing ligand (TRAIL) and transferrin, and containing …

There has been much recent progress in our understanding of the role played by the RAS–
RAF–MEK–ERK cascade in human cancer. RAS is an oncogene and this pathway is known …

Options for skin cancer treatment currently include surgery, radiotherapy, topical
chemotherapy, cryosurgery, curettage, and electrodessication. Although effective, surgery is …

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) possesses strong anti-
cancer potential because of its ability to specifically kill cancer cells. However, clinical use of …