In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

Periodontitis is a dysbiotic inflammatory disease with an adverse impact on systemic health.
Recent studies have provided insights into the emergence and persistence of dysbiotic oral …

INTRODUCTION Mucosal barrier sites are continuously exposed to diverse environmental
stimuli, and the fine-tuning of mucosal tissue–specific immune responses is key to …

Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …

The past decade of basic research in periodontology has driven radical changes in our
understanding and perceptions of the pathogenic processes that drive periodontal tissue …

The oral mucosal barrier is constantly exposed to a plethora of triggers requiring immune
control, including a diverse commensal microbiome, ongoing damage from mastication, and …

Interleukin‐17 (also known as interleukin‐17A) is a key cytokine that links T‐cell activation to
neutrophil mobilization and activation. As such, interleukin‐17 can mediate protective innate …

Recent studies have uncovered novel mechanisms underlying the breakdown of periodontal
host–microbe homeostasis, which can precipitate dysbiosis and periodontitis in susceptible …

In their classic 1976 paper, Page & Schroeder described the histopathologic events and the
types of myeloid cells and lymphocytes involved in the initiation and progression of …

Certain low-abundance bacterial species, such as the periodontitis-associated oral
bacterium Porphyromonas gingivalis, can subvert host immunity to remodel a normally …