This review focuses on the type A cytochrome c oxidases (C c O), which are found in all
mitochondria and also in several aerobic bacteria. C c O catalyzes the respiratory reduction …

Cytochrome c oxidase (CcO), the terminal oxidase of cell respiration, reduces molecular
oxygen (O2) in a reaction that is coupled with proton pumping. Since the discovery of this …

Enzyme reactions that involve strong coupling between proton and electron transfer are of
fundamental importance in biology. This is particularly evident in the reactions of primary …

Cytochrome c oxidase generates a proton motive force by two separate mechanisms. The
first mechanism is similar to that postulated by Peter Mitchell, and is based on electrons and …

A series of metalloprotein complexes embedded in a mitochondrial or bacterial membrane
utilize electron transfer reactions to pump protons across the membrane and create an …

Cytochrome c oxidase catalyzes most of the biological oxygen consumption on Earth, a
process responsible for energy supply in aerobic organisms. This remarkable membrane …

Recent time-resolved optical and electrometric experiments have provided a sequence of
events for the proton-translocating mechanism of cytochrome c oxidase. These data also set …

Cytochrome c oxidase (CcO), as the terminal oxidase of cellular respiration, coupled with a
proton-pumping process, reduces molecular oxygen (O2) to water. This intriguing and highly …

Respiratory heme-copper oxidases are integral membrane proteins that catalyze the
reduction of molecular oxygen to water using electrons donated by either quinol (quinol …

Cytochrome c oxidase (CcO) is a terminal protein of the respiratory chain in eukaryotes and
some bacteria. It catalyzes most of the biologic oxygen consumption on earth done by …