[HTML][HTML] Zinc: from biological functions to therapeutic potential

MI Costa, AB Sarmento-Ribeiro… - International Journal of …, 2023 - mdpi.com
The trace element zinc (Zn) displays a wide range of biological functions. Zn ions control
intercellular communication and intracellular events that maintain normal physiological …

[HTML][HTML] The important role of zinc in neurological diseases

Z Li, Y Liu, R Wei, VW Yong, M Xue - Biomolecules, 2022 - mdpi.com
Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …

Zinc and human health: an update

CT Chasapis, AC Loutsidou, CA Spiliopoulou… - Archives of …, 2012 - Springer
The importance of micronutrients in health and nutrition is undisputable, and among them,
zinc is an essential element whose significance to health is increasingly appreciated and …

[HTML][HTML] Mechanistic impact of zinc deficiency in human development

A Hussain, W Jiang, X Wang, S Shahid, N Saba… - Frontiers in …, 2022 - frontiersin.org
Zinc (Zn) deficiency in humans is an emerging global health issue affecting approximately
two billion people across the globe. The situation prevails due to the intake of Zn deficient …

Zinc and the modulation of redox homeostasis

PI Oteiza - Free Radical Biology and Medicine, 2012 - Elsevier
Zinc, a redox-inactive metal, has been long viewed as a component of the antioxidant
network, and growing evidence points to its involvement in redox-regulated signaling. These …

[HTML][HTML] Zinc in the brain: friend or foe?

S Choi, DK Hong, BY Choi, SW Suh - International Journal of Molecular …, 2020 - mdpi.com
Zinc is a trace metal ion in the central nervous system that plays important biological roles,
such as in catalysis, structure, and regulation. It contributes to antioxidant function and the …

[HTML][HTML] The pathophysiological role of CoA

A Czumaj, S Szrok-Jurga, A Hebanowska… - International Journal of …, 2020 - mdpi.com
The importance of coenzyme A (CoA) as a carrier of acyl residues in cell metabolism is well
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …

[HTML][HTML] Zinc in innate and adaptive tumor immunity

E John, TC Laskow, WJ Buchser, BR Pitt… - Journal of translational …, 2010 - Springer
Zinc is important. It is the second most abundant trace metal with 2-4 grams in humans. It is
an essential trace element, critical for cell growth, development and differentiation, DNA …

[HTML][HTML] Zinc promotes functional recovery after spinal cord injury by activating Nrf2/HO-1 defense pathway and inhibiting inflammation of NLRP3 in nerve cells

D Li, H Tian, X Li, L Mao, X Zhao, J Lin, S Lin, C Xu… - Life sciences, 2020 - Elsevier
Aims To study the specific therapeutic effect of zinc on spinal cord injury (SCI) and its
specific protective mechanism. Main methods The effects of zinc ions on neuronal cells were …

Neurobiology of zinc and its role in neurogenesis

V Kumar, A Kumar, K Singh, K Avasthi… - European Journal of …, 2021 - Springer
Abstract Background Zinc (Zn) has a diverse role in many biological processes, such as
growth, immunity, anti-oxidation system, homeostatic, and repairing. It acts as a regulatory …