Runs of homozygosity: current knowledge and applications in livestock

E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …

[HTML][HTML] On the concepts and measures of diversity in the genomics era

KK Kanaka, N Sukhija, RC Goli, S Singh, I Ganguly… - Current Plant …, 2023 - Elsevier
Diversity serves as the foundation for breeding and evolution. In the science of genomics,
the investigation of genetic variation has long been a prominent subject. Researchers now …

Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle

M Forutan, S Ansari Mahyari, C Baes, N Melzer… - BMC genomics, 2018 - Springer
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …

Genomic inbreeding estimation in small populations: evaluation of runs of homozygosity in three local dairy cattle breeds

S Mastrangelo, M Tolone, R Di Gerlando, L Fontanesi… - Animal, 2016 - cambridge.org
In the local breeds with small population size, one of the most important problems is the
increase of inbreeding coefficient (F). High levels of inbreeding lead to reduced genetic …

Genome-wide scan for runs of homozygosity identifies potential candidate genes associated with local adaptation in Valle del Belice sheep

S Mastrangelo, M Tolone, MT Sardina, G Sottile… - Genetics Selection …, 2017 - Springer
Background Because very large numbers of single nucleotide polymorphisms (SNPs) are
now available throughout the genome, they are particularly suitable for the detection of …

Genome-wide patterns of homozygosity provide clues about the population history and adaptation of goats

F Bertolini, TF Cardoso, G Marras, EL Nicolazzi… - Genetics Selection …, 2018 - Springer
Background Patterns of homozygosity can be influenced by several factors, such as
demography, recombination, and selection. Using the goat SNP50 BeadChip, we genotyped …

Characterization of runs of homozygosity, heterozygosity-enriched regions, and population structure in cattle populations selected for different breeding goals

HA Mulim, LF Brito, LFB Pinto, JBS Ferraz, L Grigoletto… - BMC genomics, 2022 - Springer
Background A decline in the level of genetic diversity in livestock can result in reduced
response to selection, greater incidence of genetic defects, and inbreeding depression. In …

Evolution and domestication of the Bovini species

K Zhang, JA Lenstra, S Zhang, W Liu, J Liu - Animal Genetics, 2020 - Wiley Online Library
Domestication of the Bovini species (taurine cattle, zebu, yak, river buffalo and swamp
buffalo) since the early Holocene (ca. 10 000 BCE) has contributed significantly to the …

Genome-Wide Runs of Homozygosity Revealed Selection Signatures in Bos indicus

SP Dixit, S Singh, I Ganguly, AK Bhatia… - Frontiers in …, 2020 - frontiersin.org
Genome-wide runs of homozygosity (ROH) are suitable for understanding population
history, calculating genomic inbreeding, deciphering genetic architecture of complex traits …

Variants at the ASIP locus contribute to coat color darkening in Nellore cattle

BB Trigo, ATH Utsunomiya, AAAD Fortunato… - Genetics Selection …, 2021 - Springer
Abstract Background Nellore cattle (Bos indicus) are well-known for their adaptation to warm
and humid environments. Hair length and coat color may impact heat tolerance. The Nellore …