Liver sinusoidal endothelial cells (LSECs) line the low shear, sinusoidal capillary channels
of the liver and are the most abundant non-parenchymal hepatic cell population. LSECs do …

Leukocyte migration through activated venular walls is a fundamental immune response that
is prerequisite to the entry of effector cells such as neutrophils, monocytes, and effector T …

Monocytes fundamentally contribute to immune surveillance and the inflammatory response
in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site …

Here we focus on how neutrophils have a key regulatory role in vascular inflammation.
Recent studies using advanced imaging techniques have yielded new insights into the …

The migration of neutrophils into inflamed tissues is a fundamental component of innate
immunity. A decisive step in this process is the polarized migration of blood neutrophils …

Vascular inflammation is associated with and in large part driven by changes in the
leukocyte compartment of the vessel wall. Here, we focus on monocyte influx during …

The number of leukocytes present in circulation varies throughout the day, reflecting bone
marrow output and emigration from blood into tissues. Using an organism-wide circadian …

The shuttling of leukocytes between the bloodstream and interstitial tissues involves different
locomotion strategies that are governed by locally presented soluble and cell-bound signals …

Endothelial junctions provide blood and lymph vessel integrity and are essential for the
formation of a vascular system. They control the extravasation of solutes, leukocytes and …

Endothelial cells line the lumen of all blood vessels and play a critical role in maintaining the
barrier function of the vasculature. Sealing of the vessel wall between adjacent endothelial …