Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review

P Csermely, T Korcsmáros, HJM Kiss, G London… - Pharmacology & …, 2013 - Elsevier
Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

Mixed H∞/passivity based stability analysis of fractional-order gene regulatory networks with variable delays

N Padmaja, P Balasubramaniam - Mathematics and Computers in …, 2022 - Elsevier
In this paper, we derive delay and fractional-order dependent sufficient conditions for
fractional-order gene regulatory networks (FOGRNs) with time-varying delays to be stable …

Globally asymptotic stability analysis for genetic regulatory networks with mixed delays: an M-matrix-based approach

X Zhang, L Wu, J Zou - IEEE/ACM Transactions on …, 2015 - ieeexplore.ieee.org
This paper deals with the problem of globally asymptotic stability for nonnegative equilibrium
points of genetic regulatory networks (GRNs) with mixed delays (ie, time-varying discrete …

Criteria for observability and reconstructibility of Boolean control networks via set controllability

X Zhang, M Meng, Y Wang… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
This brief focuses on observability and recontructibility of Boolean control networks (BCNs)
via the semi-tensor product of matrices. To solve the problems, for a given BCN, an …

Dynamical criticality in gene regulatory networks

M Villani, L La Rocca, SA Kauffman, R Serra - Complexity, 2018 - Wiley Online Library
A well‐known hypothesis, with far‐reaching implications, is that biological evolution should
preferentially lead to states that are dynamically critical. In previous papers, we showed that …

The energetics of cellular life transitions

AS Monzel, M Levin, M Picard - Life metabolism, 2024 - academic.oup.com
Major life transitions are always difficult because change costs energy. Recent findings have
demonstrated how mitochondrial oxidative phosphorylation (OxPhos) defects increase the …

[图书][B] Modelling protocells

R Serra, M Villani - 2017 - Springer
It took quite a long time to complete this book. More than 20 years had elapsed since I wrote
my last volume as an author, not just as an editor. And I felt it important to find again the …

Boolean networks and their dynamics: the impact of updates

L Paulevé, S Sené - Systems Biology Modelling and Analysis …, 2022 - Wiley Online Library
Boolean networks are a mathematical model that has been widely used since decades in
the context of biological regulation networks' qualitative modelling. They consist in …

M-matrix-based globally asymptotic stability criteria for genetic regulatory networks with time-varying discrete and unbounded distributed delays

X Zhang, Y Han, L Wu, J Zou - Neurocomputing, 2016 - Elsevier
The problem of globally asymptotic stability for nonnegative equilibrium points of genetic
regulatory networks (GRNs) with time-varying discrete delays and unbounded distributed …

Dynamics of fuzzy genetic regulatory networks with leakage and mixed delays in doubly-measure pseudo-almost periodic environment

M Ayachi - Chaos, Solitons & Fractals, 2022 - Elsevier
The study of dynamics behaviors of genetic regulatory networks (GRNs) is essential for the
understanding of living organisms at both molecular and cellular levels. This paper deals …