Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review
P Csermely, T Korcsmáros, HJM Kiss, G London… - Pharmacology & …, 2013 - Elsevier
Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …
methods and in rational drug design, the increase in approved drugs in the past decade did …
Mixed H∞/passivity based stability analysis of fractional-order gene regulatory networks with variable delays
N Padmaja, P Balasubramaniam - Mathematics and Computers in …, 2022 - Elsevier
In this paper, we derive delay and fractional-order dependent sufficient conditions for
fractional-order gene regulatory networks (FOGRNs) with time-varying delays to be stable …
fractional-order gene regulatory networks (FOGRNs) with time-varying delays to be stable …
Globally asymptotic stability analysis for genetic regulatory networks with mixed delays: an M-matrix-based approach
X Zhang, L Wu, J Zou - IEEE/ACM Transactions on …, 2015 - ieeexplore.ieee.org
This paper deals with the problem of globally asymptotic stability for nonnegative equilibrium
points of genetic regulatory networks (GRNs) with mixed delays (ie, time-varying discrete …
points of genetic regulatory networks (GRNs) with mixed delays (ie, time-varying discrete …
Criteria for observability and reconstructibility of Boolean control networks via set controllability
This brief focuses on observability and recontructibility of Boolean control networks (BCNs)
via the semi-tensor product of matrices. To solve the problems, for a given BCN, an …
via the semi-tensor product of matrices. To solve the problems, for a given BCN, an …
Dynamical criticality in gene regulatory networks
A well‐known hypothesis, with far‐reaching implications, is that biological evolution should
preferentially lead to states that are dynamically critical. In previous papers, we showed that …
preferentially lead to states that are dynamically critical. In previous papers, we showed that …
The energetics of cellular life transitions
Major life transitions are always difficult because change costs energy. Recent findings have
demonstrated how mitochondrial oxidative phosphorylation (OxPhos) defects increase the …
demonstrated how mitochondrial oxidative phosphorylation (OxPhos) defects increase the …
Boolean networks and their dynamics: the impact of updates
Boolean networks are a mathematical model that has been widely used since decades in
the context of biological regulation networks' qualitative modelling. They consist in …
the context of biological regulation networks' qualitative modelling. They consist in …
M-matrix-based globally asymptotic stability criteria for genetic regulatory networks with time-varying discrete and unbounded distributed delays
X Zhang, Y Han, L Wu, J Zou - Neurocomputing, 2016 - Elsevier
The problem of globally asymptotic stability for nonnegative equilibrium points of genetic
regulatory networks (GRNs) with time-varying discrete delays and unbounded distributed …
regulatory networks (GRNs) with time-varying discrete delays and unbounded distributed …
Dynamics of fuzzy genetic regulatory networks with leakage and mixed delays in doubly-measure pseudo-almost periodic environment
M Ayachi - Chaos, Solitons & Fractals, 2022 - Elsevier
The study of dynamics behaviors of genetic regulatory networks (GRNs) is essential for the
understanding of living organisms at both molecular and cellular levels. This paper deals …
understanding of living organisms at both molecular and cellular levels. This paper deals …