Engineering disease analyte response in peptide self-assembly

S Yu, MJ Webber - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
A need to enhance the precision and specificity of therapeutic nanocarriers inspires the
development of advanced nanomaterials capable of sensing and responding to disease …

Research Progress in Hydrogels for Cartilage Organoids

X Li, S Sheng, G Li, Y Hu, F Zhou… - Advanced Healthcare …, 2024 - Wiley Online Library
The repair and regeneration of cartilage has always been a hot topic in medical research.
Cartilage organoids (CORGs) are special cartilage tissue created using tissue engineering …

Glucose-driven droplet formation in complexes of a supramolecular peptide and therapeutic protein

S Yu, W Chen, G Liu, B Flores, EL DeWolf… - Journal of the …, 2024 - ACS Publications
Biology achieves remarkable function through processes arising from spontaneous or
transient liquid–liquid phase separation (LLPS) of proteins and other biomolecules. While …

Strain-Stiffening Mechanoresponse in Dynamic-Covalent Cellulose Hydrogels

RC Ollier, MJ Webber - Biomacromolecules, 2024 - ACS Publications
Mechanical stimuli such as strain, force, and pressure are pervasive within and beyond the
human body. Mechanoresponsive hydrogels have been engineered to undergo changes in …

Chiral Self‐Assembly of a Pyrene‐Appended Glutamylalanine Dipeptide and Its Charge Transfer Complex: Fabrication of Magneto‐Responsive Hydrogels and …

P Ruidas, SK Dubey, SA Hafiz, J Mandal… - Macromolecular …, 2024 - Wiley Online Library
The formation of a robust, self‐healing hydrogel of a novel pyrene‐appended dipeptide, Py‐
E‐A (L‐Glutamic acid short as E; L‐Alanine short as A) is demonstrated. Detailed studies …

Analysis of Glucose Responsive Glucagon Therapeutics using Computational Models of the Glucoregulatory System

AA Alizadehmojarad, S Yang, X Gong… - Advanced Healthcare …, 2024 - Wiley Online Library
Glucose‐responsive glucagon (GRG) therapeutics are a promising technology for reducing
the risk of severe hypoglycemia as a complication of diabetes mellitus. Herein, the …

Engineering a Pathway to Glucose-Responsive Therapeutics

MJ Webber - Diabetes, 2024 - Am Diabetes Assoc
In 2014, the American Diabetes Association instituted a novel funding paradigm to support
diabetes research through its Pathway to Stop Diabetes program. This program took a …

Analytical and drug delivery strategies for short peptides: From manufacturing to market

A Chawathe, V Ahire, K Luthra, B Patil, K Garkhal… - Analytical …, 2024 - Elsevier
In recent times, biopharmaceuticals have gained attention because of their tremendous
potential to benefit millions of patients globally by treating widespread diseases such as …

[引用][C] A squishy solution for smoother drug delivery

A Nathan