Astrocytes functionally interact with neurons and with other brain cells. Although not
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …

Calcium signaling underlies much of physiology. Almost all the Ca2+ in the cytoplasm is
bound to buffers, with typically only∼ 1% being freely ionized at resting levels in most cells …

Connexin channels are known to be permeable to a variety of cytoplasmic molecules. The
first observation of second messenger junctional permeability, made∼ 30 years ago …

The gastrointestinal (GI) tract displays multiple motor patterns that move nutrients and
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …

Persistent activity in populations of neurons, time-varying activity across a neural population,
or activity-silent mechanisms carried out by hidden internal states of the neural population …

This review provides a comparative overview of recent developments in the modelling of
cellular calcium oscillations. A large variety of mathematical models have been developed …

The interactions between mathematics and physiology have a long and illustrious history, of
which the study of calcium signalling is but a small chapter. Nevertheless, for those involved …

Ca2+ is one of the most important messengers. It transmits signals inside living cells and
takes part in intercellular coordination. The dynamics of the Ca2+ concentration shows a …

The" Virtual Cell" provides a general system for testing cell biological mechanisms and
creates a framework for encapsulating the burgeoning knowledge base comprising the …

Abstract Calcium (C a 2+), inositol trisphosphate (IP 3), and nitric oxide (NO) signaling are
essential to maintain the structural integrity and physiological activity of fibroblast cells. The …