SP-A and SP-D: dual functioning immune molecules with antiviral and immunomodulatory properties
A Watson, J Madsen, HW Clark - Frontiers in Immunology, 2021 - frontiersin.org
Surfactant proteins A (SP-A) and D (SP-D) are soluble innate immune molecules which
maintain lung homeostasis through their dual roles as anti-infectious and …
maintain lung homeostasis through their dual roles as anti-infectious and …
Surfactant protein D in respiratory and non-respiratory diseases
GL Sorensen - Frontiers in medicine, 2018 - frontiersin.org
Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …
TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis
H Wu, Y Wang, Y Zhang, M Yang… - Proceedings of the …, 2015 - National Acad Sciences
Transcription activator-like effector nuclease (TALEN)-mediated genome modification has
been applied successfully to create transgenic animals in various species, such as mouse …
been applied successfully to create transgenic animals in various species, such as mouse …
Immunomodulatory roles of surfactant proteins A and D: implications in lung disease
AM Pastva, JR Wright, KL Williams - Proceedings of the American …, 2007 - atsjournals.org
Surfactant, a lipoprotein complex, was originally described for its essential role in reducing
surface tension at the air–liquid interface of the lung; however, it is now recognized as being …
surface tension at the air–liquid interface of the lung; however, it is now recognized as being …
[HTML][HTML] Surfactant protein A and surfactant protein D variation in pulmonary disease
GL Sorensen, S Husby, U Holmskov - Immunobiology, 2007 - Elsevier
Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …
immunity. The proteins are host defense lectins, belonging to the collectin family which also …
Protective role of the lung collectins surfactant protein A and surfactant protein D in airway inflammation
A Haczku - Journal of Allergy and Clinical Immunology, 2008 - Elsevier
The acute inflammatory airway response is characterized by a time-dependent onset
followed by active resolution. Emerging evidence suggests that epithelial cells of the …
followed by active resolution. Emerging evidence suggests that epithelial cells of the …
Comprehensive characterisation of pulmonary and serum surfactant protein D in COPD
C Winkler, EN Atochina-Vasserman, O Holz… - Respiratory …, 2011 - Springer
Background Pulmonary surfactant protein D (SP-D) is considered as a candidate biomarker
for the functional integrity of the lung and for disease progression, which can be detected in …
for the functional integrity of the lung and for disease progression, which can be detected in …
Surfactant protein D in human lung diseases
D Hartl, M Griese - European journal of clinical investigation, 2006 - Wiley Online Library
The lung is continuously exposed to inhaled pollutants, microbes and allergens. Therefore,
the pulmonary immune system has to defend against harmful pathogens, while an …
the pulmonary immune system has to defend against harmful pathogens, while an …
The amazing innate immune response to influenza A virus infection
S Tripathi, MR White, KL Hartshorn - Innate immunity, 2015 - journals.sagepub.com
Influenza A viruses (IAVs) remain a major health threat and a prime example of the
significance of innate immunity. Our understanding of innate immunity to IAV has grown …
significance of innate immunity. Our understanding of innate immunity to IAV has grown …
Innate defense against influenza A virus: activity of human neutrophil defensins and interactions of defensins with surfactant protein D
KL Hartshorn, MR White, T Tecle… - The Journal of …, 2006 - journals.aai.org
Abstract Surfactant protein D (SP-D) plays important roles in innate host defense against
influenza A virus (IAV) infection, in part by modifying interactions with neutrophils. Human …
influenza A virus (IAV) infection, in part by modifying interactions with neutrophils. Human …